Methods: Amide and mix-type bonds compounds were synthesized by conjugated the amino groups and acid groups with hydroxyl or acid links.

方法：四种药物通过酯化、酰胺反应由不同的连接子合成酰胺类和混合键类互联体前药。

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Methods: Amide and mix-type bonds compounds were synthesized by conjugated the amino groups and acid groups with hydroxyl or acid links.

方法：四种药物通过酯化、酰胺反应由不同的连接子合成酰胺类和混合键类互联体前药。

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