The genotype and allele frequency of ALDH2 in alcoholic cardiomyopathy group and alcohol dependent group were no difference.
嗜酒组和酒精性心肌病组各种基因型频率及等位基因的频率无统计学差异。
In male ALDH2 genotype carriers, the risk for gastric cancer was 2.69 times in alcohol consumers comparing with no alcohol consumers.
在携带ALDH2谷氨酸纯合型的男性中，饮酒者发生癌的危险性是不饮酒者的2.69倍。
Conclusion The genetic polymorphisms of ALDH2 might contribute to gastric cancer susceptibility and interact with environmental exposure.
结论ALDH2基因多态性与胃癌易感性有关，并与环境暴露有一定的交互作用。
Conclusion the active ALDH2 might be one of the factors influencing the individual susceptibility to TCE - induced medicamentosa-like dermatitis.
结论高活性ALDH2可能是导致三氯乙烯药疹样皮炎个体易感性差异的原因之一。
An ALDH2-deficient person who has two beers a day has six to 10 times the risk of developing esophageal cancer as a person not deficient in the enzyme.
和没有ALDH2缺陷的人相比，该基因缺陷的人每天喝2杯啤酒会使患食管癌的风险增加6- 10倍。
To find out a method which is more convenient, cost-saving and enough accurate to detect genotypes of alcohol dehydrogenase 2 (ADH2)and aldehyde dehydrogenase 2 (ALDH2).
为获得更为简便经济同时精确度足够高的酒精脱氢酶2 （ADH2 ）和乙醛脱氢酶2 （ALDH2 ）基因多态型测定的新方法。
Objective: To study the relationship between aldehyde dehydrogenase-2 (ALDH2) G1951A gene polymorphism and obstructive sleep apnea hypopnea syndrome (OSAHS) in male drinkers.
目的：了解男性饮酒者乙醛脱氢酶(ALDH2)基因g1951 A多态性与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的关系。
CONCLUSION: the reduction of ALDH2 activity might increase the susceptivity of myocytes to apoptosis following hypoxia, suggesting a protective role of ALDH2 in hypoxia-induced myocardial injury.
结论：ALDH2酶活性降低可增加心肌细胞对缺氧导致凋亡的易感性，ALDH2对缺氧引起的细胞凋亡有拮抗作用。
CONCLUSION: the reduction of ALDH2 activity might increase the susceptivity of myocytes to apoptosis following hypoxia, suggesting a protective role of ALDH2 in hypoxia-induced myocardial injury.
结论：ALDH2酶活性降低可增加心肌细胞对缺氧导致凋亡的易感性，ALDH2对缺氧引起的细胞凋亡有拮抗作用。
应用推荐