First, feeding experiment and resting cell system were used to confirm precursors of AGPM.
首先，采用刺激实验和静息细胞培养实验法来确定AGPM的合成前体。
So the polyketide pathway was presumed to be the main biosynthetic pathway of antibiotic AGPM.
所以聚酮途径被认为是抗生素agpm合成的主要途径。
To improve antibiotic AGPM production, the regulation of glucose, ammonium, and phosphate was studied.
探讨了葡萄糖、铵离子及磷酸盐对抗生素agpm生物合成的调控作用和机理。
Polyketide pathway was therefore confirmed as the main biosynthetic pathways of antibiotic AGPM by evidence both pro and con.
从而从正反两面都证明了抗生素AGPM由聚酮途径合成。
To increase its production and obtain new pharmaceuticals of similar structure, the novel antibiotic AGPM biosynthesis and regulation mechanism was studied in this dissertation.
为了提高新型抗生素agpm的生产以及获得类似结构新药物，本论文首次开展其生物合成和调控机制的研究。
According to the strain breeding theory, the selection and breeding of antibiotics AGPM producing mutant and the fermentation technology of AGPM were systematically studied in this thesis.
本文根据育种理论，对新型抗肿瘤抗生素agpm生产菌种的选育、发酵法生产抗生素agpm进行了系统的研究。
According to the strain breeding theory, the selection and breeding of antibiotics AGPM producing mutant and the fermentation technology of AGPM were systematically studied in this thesis.
本文根据育种理论，对新型抗肿瘤抗生素agpm生产菌种的选育、发酵法生产抗生素agpm进行了系统的研究。
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