Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).

酪氨酸576和酪氨酸577处于激酶结构域的激活环，这些残基的突变减弱FAK的催化活性（6）。

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Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).

酪氨酸576和酪氨酸577处于激酶结构域的激活环，这些残基的突变减弱FAK的催化活性（6）。

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