目的介绍国内鼻腔给药新制剂的研究进展。
Objective To review the advances in nasal drug delivery systems.
鼻腔给药是一种极具潜力的药物转运系统。
目的介绍国内鼻腔给药新制剂的研究进展。
Progress in research of new dosage forms for nasal administration;
目的介绍用于全身治疗的鼻腔给药系统研究概况。
OBJECTIVE To introduce the general investigation of nasal drug delivery system for therapy.
在鼻腔给药后在小鼠的大脑中检测到了大量的外泌体。
A considerable amount of exosomes was detected in PD mouse brain following intranasal administration.
目的：探讨鼻腔给药治疗脑血管疾病的可行性和可能的作用机制。
AIM To study the feasibility and possible action mechanism of the treatment of cerebrovascular disease with intranasal administration.
原位凝胶用于鼻腔给药系统具有较好的应用前景，值得深入开发研究。
In situ gel for nasal drug delivery system has a good prospect, deserving in-depth development research.
目的研究盐酸川芎嗪(TMPH)经大鼠鼻腔给药后的脑内药动学特性。
OBJECTIVE To investigate the brain pharmacokinetics of tetramethylpyrazine hydrochloride (TMPH) after intranasal administration in rats.
本文结合鼻腔的生理和给药的特点，综述了近年来鼻腔给药剂型的研究进展。
This article reviewed the progresses in the research of new dosage forms for nasal administration.
结论药代动力学和药效学结果证明，三七总皂苷鼻腔给药制剂具有很好的开发前景。
Conclusion The results of pharmacokinetics and pharmacodynamics demonstrated that PNS intranasal preparation has a pretty prospect to develop.
目的研究壳聚糖纳米粒作为蛋白类疫苗的新载体，并评价其鼻腔给药后所产生的免疫效果。
OBJECTIVE to prepare Chitosan nanoparticles (NPs) as new carriers for vaccine delivery and to evaluate the effect of this system on the immune response for intranasal delivery.
并应用此模型采用同样方法研究NGF静脉给药，NGF和NGF-SSL鼻腔给药后的药效。
The pharmacodynamic parameters of NGF (iv) and NGF, NGF-SSL (na) were studied by using the AD model.
摘要：目的制备地西泮固体脂质纳米粒，评价其制剂学性质，并探讨其经鼻腔给药后的药动学过程。
ABSTRACT: OBJECTIVE To prepare diazepam solid lipid nanoparticles, evaluate the pharmacy characters and study the pharmacokinetics after intranasal administration.
结论鼻腔给药能够实现药物给药途径上的脑靶向，药物经脂质体包载后能明显增加其脑摄入，提高药效。
CONCLUSION Nasal administration is a better way to target the brain, and the brain uptake of drug modified with lioposomes would be increased, the pharmacodynamics would be improved.
现从药物由鼻腔到脑的转运方式、影响因素、剂型、评价方法以及增强脑靶向性的方法等方面，对近年来鼻腔给药脑靶向性的研究进展进行综述。
Advances on drugs transport pathway from nasal cavity to brain, factors affecting the transport of drugs, types of dosage forms and evaluation tools of the brain-targeted nasal delivery system we...
重组水蛭素鼻腔喷雾剂长期给药对鼻黏膜结构有一定影响，但此作用可在停止给药后恢复。
HVS was able to damaged the nasal epithelium, but this effect recovered soon after sloping administration.
本文重点介绍了一些新的给药途径和给药系统，例如鼻腔、颊等给药途径以及黏膜给药系统、透皮给药系统、缓控释技术等给药系统的进展。
The effect of buccal mucosa in different regions on penetration and absorption of drugs, various and quality evaluation methods of buccal mucosa drug delivery system are introduced.
本文重点介绍了一些新的给药途径和给药系统，例如鼻腔、颊等给药途径以及黏膜给药系统、透皮给药系统、缓控释技术等给药系统的进展。
The effect of buccal mucosa in different regions on penetration and absorption of drugs, various and quality evaluation methods of buccal mucosa drug delivery system are introduced.
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