MTT法检测融合蛋白对黑色素瘤细胞的体外抑制率。
The inhibition ratio of the fusion protein was tested by MTT method.
目的:获得表达HLA -DR基因的小鼠黑色素瘤细胞。
Objective: Obtaining mouse melanoma cells expressing HLA DR genes.
目的:研究紫外线照射对小鼠B16黑色素瘤细胞凋亡率的影响。
Objective:To investigate the apoptotic rate of murine B16 melanoma cells induced by ultraviolet radiation(UV).
目的观察5 -脂氧合酶抑制剂对黑色素瘤细胞产生金属蛋白酶的作用。
Aim to study the effects of5 lipoxygenase inhibitors on the production of matrix metalloproteinases of melanoma cells.
目的探讨PEX基因在体外对鼠黑色素瘤细胞B16 F10生物学性状的影响。
Objective To study the effects of PEX gene on the biological characters of mouse melanoma cells (B16F10) in vitro.
方法利用层粘连蛋白糖肽影响血清诱导的小鼠b16黑色素瘤细胞凝集及其实验性转移。
Methods The experimental lung metastasis and tumor cell aggregation of B16 murine melanoma cells were quantified.
目的:探讨紫杉醇体外抑制人黑色素瘤细胞(A375细胞)增殖及诱导凋亡作用机制。
Objective: to investigate the growth-inhibitory and apoptosis-inducing effect of paclitaxel on human melanoma A375 cell and its mechanism in vitro.
推测pten基因的正常表达在抑制脉络膜黑色素瘤细胞的聚集黏附过程中具有重要作用。
Normal expression of PTEN may play an important role in suppressing focal adhesion formation, spreading and migration of melanoma cells.
目的研究次级淋巴组织趋化因子(SLC)基因转染对小鼠恶性黑色素瘤细胞生物学特性的影响。
Objective To investigate the effects of secondary lymphoid organ chemokine (SLC) gene transfer on the biological characteristics of murine melanoma cells.
通过流式细胞术定量研究和蛋白酶活性分析,对具有不同潜在转移能力的人黑色素瘤细胞进行研究。
Methods FCM and the zymography were used to study the human melanoma cell lines with different metastatic potential.
目的:研究大蒜提取物二烯丙基二硫化物(DADS)对小鼠黑色素瘤细胞B16的生长抑制作用。
Objective: To elucidate the effects of diallyl disulfide (DADS), an oil-soluble organosulfur compound found in garlic, in suppressing the growth of B16 cells.
结果:APS能促进巨噬细胞NO合成,并能显著增强小鼠腹腔巨噬细胞对黑色素瘤细胞的杀伤作用。
Results: APS could significantly increase no synthesis and enhance the effects of mice peritoneal macrophage on killing carcinoma cells.
对它们生物学性质的检测,发现它们都能杀伤黑色素瘤细胞,但缺乏抑制无细胞蛋白质生物合成的能力。
Their hydrophobic properties were similar to each other. As for their biological properties, they could kill some cancer cells like cells of melanocytoma.
目的探讨白细胞介素12(IL12)基因转移对弱免疫原性的小鼠B16黑色素瘤细胞生长与转移的影响。
Objective To study the tumorigenicity and metastasis of poorly immunogenic murine B16 melanoma cells transfected with murine interleukin12 (IL12) gene.
PCL能抑制某些癌瘤细胞的生长,在测试的几种细胞中,对人黑色素瘤细胞m 21生长的抑制较为明显。
PCL had shown the inhibiting effect on growth of several tumor cells. Among the cells tested the effect on human melanoma M21 were shown to be the most strongly inhibited.
研究人员用一段被他们进行基因编码的基因重组病毒感染T细胞,这段基因编码是能够识别黑色素瘤细胞的受体蛋白的。
They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.
Plexxikon之所以能开发出这种药物,是因为研究人员利用基因测序仪绘出了黑色素瘤细胞的基因组,并发现了一个关键的突变。
Plexxikon was able to develop the drug because researchers using a gene sequencing machine had mapped the genomes of melanoma cells and found a key mutation.
有一种疫苗,肽类gp100:209-217(210M),体外实验已经显示出激活高水平的可以识别并攻击黑色素瘤细胞的T细胞。
One vaccine, the peptide gp100:209-217(210M), has been shown to elicit very high levels of T cells that recognize and attack melanoma cells in vitro.
目的研究新维甲类化合物4-乙酰胺苯基维甲酸酯(4-APR)对B16-F10小鼠黑色素瘤细胞侵袭能力的抑制作用,探讨其作用机理。
Objective To study the inhibitory effect of new retinoid 4 acetamidophenyl retinoate (4 APR) on the reconstituted basement membrane invasion by B16 F10 mouse melanoma cells and its mechanism.
结果对于小鼠黑色素瘤细胞B16,所有虫草菌HK-1提取物的细胞毒作用均比天然虫草提取物的作用强,其中以醋酸乙酯提取物的细胞毒作用最强。
Results All of the extracts from the cultivated Cs fungus HK-1 had much stronger cytotoxicity on B16 than those from natural Cs, and the EtOAc extract had the most potent activity.
将近半数的黑色素瘤患者都有BRAF基因突变,从而导致黑色素肿瘤细胞继续生长。
About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.
2008年举行活动这天确诊的病例中,3000多例为基底细胞癌(非黑色素瘤类),354例为恶性黑色素瘤,这是最致命的皮肤癌类型。
Of the cases identified on the campaign day in 2008, more than 3000 were basal cell carcinomas (non-melanomas) and 354 were malignant melanomas, the most deadly type of skin cancer.
在实验室,他们用病毒感染那些细胞,这种病毒携带有能产生T细胞受体的基因,在这个例子中,实质上就是产生黑色素瘤导归器的基因。
In the lab, they infected those cells with a virus carrying genes that create T-cell receptors, essentially homing devices for, in this case, melanoma.
从罹患黑色素瘤的3人身上采得的肿瘤样本显示,纳米粒子找到了进入肿瘤细胞的方式。
Tumor samples taken from three people with melanoma showed the nanoparticles found their way inside tumor cells.
淋巴瘤、白血病、恶性黑色素瘤和肉瘤都开始于极微小的事件——一个细胞发生了变异(用拉丁语说,就是omniscellulae cellula e cellula)。
Lymphomas, leukemias, malignant melanomas, sarcomas all begin with that microscopic accident, a mutation in one cell: omnis cellula e cellula e cellula.
一组小鼠接种了人乳腺癌细胞,另一组则是黑色素瘤。
One set of mice was implanted with human breast cancer cells, the other with melanoma tumors.
研究者试图描述其他皮肤癌特殊皮肤气味的特征,比如鳞状上皮细胞癌及黑色素瘤等最严重的皮肤癌。
The researchers plan to characterize skin odor profiles associated with other forms of skin cancer, including squamous cell carcinoma and melanoma, the most serious form of skin cancer.
它表现出了对肿瘤细胞有毒性而对正常细胞则无,并且这种药物对乳腺癌和黑色素瘤的细胞及动物模型的已经表现出了治疗有效性。
These have been shown to be toxic to cancer cells and not to normal cells, and have already been shown to effectively treat cellular and animal models of breast cancer and melanoma.
“我们中的许多人认为,包含了免疫系统攻击癌细胞的这一联合治疗方法,最终将被证明对控制癌症最有效,如恶性黑色素瘤”,他说。
"Many of us believe that a combined approach that includes an immune system attack on cancer cells will ultimately prove to be most useful in controlling cancers such as melanoma," he tells WebMD.
小细胞癌常无明显的大核仁(而恶性黑色素瘤常有),偶尔伴有核内假包涵体。
Small cell carcinomas usually do not show large prominent nucleoli, whereas melanomas often do, accompanied by occasional intranuclear pseudoinclusions.
应用推荐