目的探讨建立一种高通量的筛选DNA加合物结合位点的方法。
Objective To develop a high throughput method of screening the binding site of DNA adducts.
目的建立一种用于体外溶栓活性精确定量分析和高通量溶栓药物筛选鉴定的方法。
OBJECTIVE To establish a method for detecting and analyzing fibrinolysis activity in vitro and high throughput screening fibrinolysis drugs.
本发明涉及一种适用于高通量药物筛选的蛋白质芯片，及其制备技术及其检测方法。
The present invention relates to a protein chip applicable to high-flux medicine screening process, its preparation technique and detection method.
本课题取得的其他研究结果有：建立了高通量筛选耐高温葡聚糖酶的方法；
The other results of the project include establishing the high-throughput screening method of beta-glucanase;
方法建立稳定的GLP-1受体激动剂高通量筛选模型，从天然药物中筛选活性成分；在PC12细胞中验证GLP-1受体激动剂的功能及作用机制。
METHODS Natural products were collected to screen in the stable cell line of GLP-1 receptor, and the active component was identified in the PC12 cells.
方法以L -羟脯氨酸为原料，合成一系列神经氨酸酶抑制剂，并用高通量活性筛选方法检测其对神经氨酸酶的抑制活性。
METHODS a series of pyrrolidine derivatives were synthesized from L-hydroxyproline, and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening.
本发明的方法成本低、高通量、覆盖率高。可用于新型保护性抗原及药物靶标的筛选。
The method of the invention has low cost, high flux and high coverage rate, and can be used in the filtration of new protection antigens and medicine targets.
探索高通量分析方法，进行氨基寡糖系列化合物的结构与代谢研究、药物动力学多合一筛选。
In exploring of high-throughput pharmacokinetic study, we profiled the isovalertatine family aminooligosaccharides and tried the cassette dosing in pharmacokinetic screening of drug candidates.
探索高通量分析方法，进行氨基寡糖系列化合物的结构与代谢研究、药物动力学多合一筛选。
In exploring of high-throughput pharmacokinetic study, we profiled the isovalertatine family aminooligosaccharides and tried the cassette dosing in pharmacokinetic screening of drug candidates.
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