中央的有核红细胞细胞质中含有嗜碱性点彩，提示骨髓毒性损伤，如铅中毒。
The nucleated RBC in the center contains basophilic stippling of the cytoplasm. This suggests a toxic injury to the bone marrow, such as with lead poisoning.
目的：研究氡及其子体和苯对小鼠血液和脂质过氧化以及骨髓毒性的联合作用及其类型，为进一步探讨二者联合毒作用的机理提供实验依据。
Objective: To study the joint effects of radon and benzene on the blood and bone marrow of mice to provide experimental data for further study.
该型消毒剂急性经口毒性为实际无毒级，对小鼠骨髓嗜多染红细胞无致微核作用，弱蓄积性。
It was actually nontoxic by acute oral toxicity test, did not cause micronucleus formation in mouse bone marrow polychromatic erythrocytes and had weak cumulative effect.
本文以小鼠骨髓嗜多染红细胞微核率（PCEMNR）为指标，测定了抗病毒性肝炎新药紫红獐牙莱的提取物对哺乳动物遗传物质的诱变作用。
The micronuclei rate of polychromatic erythrocytes of mouse bone marrow (PCEMNR) was used as an index to study the effect of S. punicea Hemsl, a new anti-hepatitis drug, on genetic material of mammal.
方法对骨髓源性神经干细胞的培养上清分别进行无菌试验、支原体检测、热原质检测和异常毒性试验。
Methods Sterility test, mycoplasma detection, pyrogen detection and abnormal toxicity test were performed respectively on culture supernatant of neural stem cells from bone marrow.
主要剂量限制性毒性为骨髓抑制。
目的：观察骨髓基质细胞条件液对PC 12细胞生长与分化的影响，分析其能否保护PC 12细胞免受鱼藤酮的毒性作用。
AIM: To study the effects of marrow stromal cells conditioned medium (CM) on proliferation and differentiation of PC12 cells, meanwhile whether CM can protect PC12 cell from the damage of rotenone.
毒性反应主要表现为骨髓抑制20例(95.2%)及胃肠道反应19例(90.5%)。
The main side effects were suppression of bone marrow 20 patients (95.2%), gastrointestinal adverse effects 19 (90.5%).
本文对杀虫净进行了大鼠急性经口毒性、小鼠骨髓微核试验和大鼠90天喂饲试验。
The toxic effect of SCJ including acute toxicity (rats), bone marrow MCN (mice) and a 90-day feeding test (rats) were studied.
研究了2，4-甲苯二异氰酸酯对小鼠的急性经口的毒性以及其对小鼠骨髓嗜多染红细胞微核率的影响。
Studied the acute toxicity effect of 2,4tolylene diisocyanate on mice by mouth and the influence of micronucleus frequency of mice bone marrow.
进行了小白鼠的急性毒性试验、蓄积毒性试验、小白鼠的骨髓细胞微核试验、睾丸染色体畸变试验及鼠伤寒沙门氏菌的致突变试验。
The Study included five experiments, i. e, acute toxicity test and accumulative test of rats, bone-marrow micronucleus test and testis chromosomal aberration test of mouse, and Ames test.
腹腔化疗的副反应除了有胃肠道反应、肾脏毒性作用、骨髓抑制外，腹痛症状较为明显。
The most common toxic and side-effects noted with intra-abdominal-chemotherapy contains disturbances of the digestive tract, toxicity of kidney, bone marrow depression and especially abdominal-pain.
本化疗方案的剂量限制毒性为骨髓抑制，其中72 %的病人发生3～4度中性粒细胞下降。
The dose limiting toxicity ssociated with this regimen was myelo suppression with grade 3~4 neutrocytopenia in 72 % of patients.
结论：不同脏器细胞对氢醌的易感性不同，肝、肾、骨髓、外周血淋巴细胞可能是氢醌的遗传毒性靶细胞。
Conclusion: There is a different susceptibility to HQ in various organs. Hepatic cells, renal cells, marrow cells, and peripheral blood lymphocytes may be the target cells of HQ genotoxicity.
吡喃阿霉素的毒性主要是骨髓抑制，但脱发率相对较低，心脏毒性、肝肾功能损害轻微。
Myelosuppression was main toxicity of Pirarubicin, but alopecia was relatively slight and cardiac, liver, renal toxicity were mild.
目的：研究MOD方案对难治性、复发性多发性骨髓瘤(MM)的疗效和毒性反应。
Objective to study the effect and toxicity of MOD regimen in treatment of refractory or recurrent multiple myeloma (MM).
主要毒副反应为骨髓抑制、胃肠道反应、周围神经毒性及静脉炎。
The main side effects were myelosuppresion, gastrointestinal reation and peripheral nerve toxicity and phlebitis.
长期接触苯可引起骨髓细胞毒性，引起外周血细胞减少、再生障碍性贫血甚至白血病等多种造血系统功能紊乱。
It has been reported that chronic exposure to benzene leaded to the reduction of blood cells, bone marrow suppression, even aplastic anemia and leukemia.
采用骨髓嗜多染细胞微核实验、致敏实验、以及细胞毒性实验对复合材料进行生物相容性评价。
Biocompatibility of the composites was evaluated by mouse micronucleus test, guinea pig sensitization test, in vitro cytotoxicity test respectively.
部分病人有一过性发热及局部红肿，但无心、肝、肾及骨髓等器官毒性作用。
In the meantime, transient fever in a few patients and local swelling in the injected sites were noted. No other form of organ toxicity was found.
主要毒性为骨髓抑制，及消化道反应。
Side effects were mainly myelo suppression and digestive tract reaction.
以FZK为受试物，通过小鼠经口急性毒性实验、小鼠骨髓细胞微核实验、小鼠骨髓细胞染色体畸变实验等毒理学实验对FZK的毒性进行了评价。
The toxicity of FZK was evaluated by acute toxicity test, micronucleus test of bone marrow cells in mice, and chromosomal aberration test of bone marrow cells.
毒性观察显示，表阿霉素为主方案的骨髓和消化道毒性低，心脏损害轻，适于伴心功不全或心电图异常患者使用。
The results show that epirubicin chemotherapy regimens were effective and were suitable to the patients with heart failure or abnormal electrocardiogram(ECG).
研究人员让小鼠中的这些骨髓细胞接触不同浓度的1，4-BQ，结果发现它诱导细胞毒性，从而导致自杀性细胞死亡，或者说细胞凋亡。
The researchers exposed mouse bone marrow cells to different concentrations of 1,4-BQ and found it induced cytotoxicity that leads to suicidal cell death, or apoptosis.
该方案的毒性不良反应主要为脱发36例（85.7%），骨髓抑制29人（69.1%），周围神经炎10例（23.9%）。
The mainly adverse events of chemotherapy were alopecia for 36 cases (85.7%), myelosuppression for 29 cases (69.1%), Peripheral neuritis for 10 cases (23.9%).
它对血细胞的毒性作用已得到很好地记载，而且已知它导致不同类型的白血病、多发性骨髓瘤和非霍奇金淋巴瘤。
Its toxic effects on blood cells are well documented and it's known to cause different kinds of leukaemia, multiple myeloma and non-Hodgkin lymphoma.
它对血细胞的毒性作用已得到很好地记载，而且已知它导致不同类型的白血病、多发性骨髓瘤和非霍奇金淋巴瘤。
Its toxic effects on blood cells are well documented and it's known to cause different kinds of leukaemia, multiple myeloma and non-Hodgkin lymphoma.
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