其病因是骨髓中异常的血浆细胞大量增殖和积累,进而破坏骨骼和身体其他组织,最后摧毁整个免疫系统。
It develops when abnormal plasma cells in bone marrow multiply and accumulate, eventually damaging bones and other tissues in the body, and finally overwhelming the immune system.
在早先的研究中,斯普金思发现白血病细胞和其它一些固态肿瘤细胞在骨髓里创建特殊的栖身处所,并在那里增殖和传播。
In prior studies, Sipkins found that leukemia cells and some solid tumors create specific niches in the bone marrow where they multiply and spread.
目的探讨地塞米松对体外培养的骨髓基质细胞增殖和分化等生物学特性的影响。
OBJECTIVE: To investigate the effects of dexamethasone on the proliferation and differentiation of bone marrow stromal cells.
目的:探讨体外培养骨髓细胞分泌促血管生长因子的能力及培养上清对内皮细胞增殖的影响。
Objective To define in vitro whether bone marrow mononuclear cells (BM MNC) secrete vascular endothelial growth factor (VEGF) and to evaluate the effect of BM MNC on endothelial cell proliferation.
目的:研究雌激素对大鼠骨髓基质细胞增殖和分化的影响,探讨其对成骨的影响。
Objective: to study the effect of estrogen on proliferation and differentiation of rat bone marrow stromal cells and to explore the mechanism of stimulation of bone formation by estrogen.
本研究探讨人参二醇(PDS)对正常人骨髓cd 34 +细胞的促进增殖和诱导分化作用。
The study was purposed to investigate the effects of the panaxadiol saponin (PDS) from Ginseng on proliferation and differentiation of human CD34 + cells from human bone marrow.
成年鼠肝无细胞液则对造血细胞的增殖无刺激活性,不能促进化疗后小鼠骨髓中造血干细胞恢复。
There was no proliferation stimulating activity on the hematopoietic cells in ALL, and the recovery of the hematopoietic stem cells in murine marrow after chemotherapy could not be promoted.
小鼠骨髓内皮细胞经过长期培养后,已转化为内皮细胞株,已传代20次,其增殖能力没有减退。
Murine bone marrow endothelial cell line could be established after long time culture and there is no significant reduction in their proliferation potency after 20 passages.
目的了解冻干骨和羟基磷灰石对骨髓间充质干细胞增殖的影响,为细胞移植载体的选择提供依据。
Objective To investigate the effect of the freeze dried bone and hydroxyapatite on the proliferation of bone marrow mesenchymal stem cells.
结果:二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用,但抑制细胞的分化。
Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.
结果:枸杞组对骨髓细胞增殖反应明显增强,与对照组相比有非常显著性差异(P<0 .01) ,而枸杞组IL-1与对照组相比无显著性差异(P>0 .0 5 )。
Results: Proliferation of bone marrow cells enhanced obviously in test group (P<0.01) compared with control group. There's no obvious IL 1 change between two groups (P>0.05).
探讨了丙二醛对体外培养人骨髓间充质干细胞的生长与增殖状态的影响及其作用机制。
The effects of malondialdehyde on the growth and proliferation of human bone marrow mesenchymal stem cells were studied.
结论骨髓间充质干细胞可有效分离,体外培养表现出旺盛的增殖能力。
Conclusion Human bone marrow mesenchymal cells were successfully isolated, and they showed active proliferation capacity in vitro.
目的了解TPO模拟肽L203对骨髓抑制后大鼠的促血小板生成作用及对大鼠巨核细胞分化、增殖的影响。
Objeactive To research on TPO analogue peptide L203 to the thrombopoiesis effective and cultural megakaryocyte differentiation, the multiplication influence in myelosuppressive rats.
骨髓单个核细胞具有分化、增殖,在缺血部位可形成大量的新生小血管的特性。
Bone marrow mononuclear cells can differentiate, proliferate, and eventually formate a large number of new small blood vessels in the ischemic area.
本文报道了云产三七根粗提物—生三七人参皂甙对小鼠骨髓细胞体外培养有促进细胞团增殖的作用。
This paper reports that raw ginsenoside, extract from panax notoginseng from Yunnan province, could promote the proliferation of routine bone marrow cells in vitro.
目的:分离培养人骨髓间充质干细胞,研究其在体外生长增殖的生物特性。
AIM: to culture mesenchymal stem cells (MSCs) derived from human bone marrow, and to study their biological features of growth and proliferation in vitro.
目的研究针刺或艾灸膈俞穴对低白模型大鼠提升白细胞和增强骨髓增殖功能的作用。
Objective To investigate the efficacy of point Geshu acupuncture or moxibustion for raising leukocyte and promoting marrow proliferation.
结论鸡血藤可刺激小鼠骨髓细胞增殖,并能提高IL - 1, IL - 2,IL - 3的分泌能力,但对脾细胞增殖没有明显影响。
CONCLUSION Caulis Spatholobi decoction improved the production of IL-1, IL-2 and IL-3. It also significantly improved the proliferative ability of bone marrow cells.
作用在两骨段的牵张力促进或激发了成骨细胞和骨髓间充质干细胞的增殖和分化从而实现骨的再生。
Osteoblasts are the main effect cells in bone formation, and bone marrow-derived mesenchymal stem cells (BMSCs) can differentiate into them under a certain degree of external stress.
结果流式细胞术证明,MSC具有间充质细胞的特征。原代及传代培养显示,胎儿骨髓msc具有活跃增殖的能力。
Results Flow cytometry analysis showed that fetal bone marrow derived MSC exhibited the characteristics of mesenchymal cells, MSC had an active proliferative ability in primary and passage cultures.
骨髓间质干细胞具有强大的增殖能力和多向分化潜能。
Bone marrow mesenchymal stem cells have great potential ability of multi-directional differentiation and reproductive activity.
采用四甲基偶氮唑盐法对大鼠牙髓干细胞和骨髓间充质干细胞的生长及增殖能力进行检测比较。
Methyl thiazolyl tetrazolium (MTT) method was used to compare the ability of growth and proliferation between rat dental pulp stem cells and marrow mesenchymal stem cells.
结论:骨髓浆细胞增殖及尿链蛋白产生可能是多发性骨髓瘤肾脏损害的主要原因。
Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma.
本文旨在研究泰和乌骨鸡活性肽对小鼠骨髓细胞的增殖作用。
The present study aimed at exploring the effect of Taihe Black-bone silky fowl active peptides on the proliferation of bone marrow cells from mice.
目的:体外观察人骨髓间充质干细胞对再生障碍性贫血患者T细胞增殖的影响。
OBJECTIVE: To explore effects of human BMSCs on t cell proliferation in patients with aplastic anemia in vitro.
结果骨髓基质细胞能在BGC、PLA 上贴附、繁殖,其生长及功能不受影响,并且BGC具有一定的促细胞增殖作用。
Results BMSCs could be attached to and extended on both BGC and PLA, and normally grown, proliferated, had active function. BGC could promote cell proliferation.
结论:同一孔池中培养,NS1骨髓瘤细胞抑制DC的增殖和功能。
Conclusion: NS1 myeloma cells could depress the proliferation and function of DC in the same cultured Wells in vitro.
目的:探讨槐耳浸膏对骨髓瘤细胞株prmi8226细胞增殖和凋亡的影响。
Objective: to investigate the effects of PS-T on proliferation and apoptosis of Myeloma cell line PRMI8226 in vitro.
目的:探讨槐耳浸膏对骨髓瘤细胞株prmi8226细胞增殖和凋亡的影响。
Objective: to investigate the effects of PS-T on proliferation and apoptosis of Myeloma cell line PRMI8226 in vitro.
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