目的观察孕激素对离体成骨细胞骨钙素基因表达及其合成的影响。
Objective To investigate the effect of progestin on the gene expression and production of osteocalcin in vitro in fetal rat calvarial osteoblasts.
结论:尼尔雌醇可以抑制IL6基因表达,从而抑制破骨细胞骨吸收,减少骨量丢失。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
结论孕酮从基因水平调节离体胎鼠成骨细胞骨钙素的生成,这种调节呈现时间及剂量依赖。
Conclusion progesterone was involved directly in osteocalcin production by regulating gene expression and this effect of progesterone was time and dose dependent.
目的探讨喂饲补肾中药大鼠血清在成骨细胞破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Objective To investigate the effects of serum from kidneytonifing traditional Chinese drugfed rats on the osteoclasts in the osteoblastosteoclast coculture system.
结果:高龄人群成骨细胞骨形成作用和破骨细胞骨吸收作用对骨骼的影响都逐渐下降,但表现出不同的特点。
RESULTS:Osteoblasts and osteoclasts changed with different features in the elderly population, although their influences on bone formation and bone resorption were declined gradually.
目的探讨血小板衍生生长因子(PDGF) -BB在成骨细胞-破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Objective to investigate the biological effects of platelet-derived growth factor (PDGF) -bb on the osteoclasts in the osteoblast-osteoclast co-culture system.
成骨细胞分化所需的第二个重要转录因子是一种具有锌指结构的,对骨形成十分重要的转录因子。
A second important transcription factor required for osteoblastic differentiation is osterix.
研究人员决定研究骨钙素(造骨细胞产生的蛋白质)的作用。
The researchers decided to examine the role of osteocalcin, a protein produced by osteoblasts.
骨诱导活性是指移植组织通过诱导受体组织的间充质细胞向成骨细胞分化。
The latter is a process whereby the transplanted tissue induces mesenchymal cells of the recipient to differentiate into osteoblastic cells.
在用DFDBA和自体骨治疗时,移植物扮演了诱导成骨细胞转化和增殖的角色。
In the case of DFDBA and autogenous bone, components of the graft act to induce osteoblastic transformation and proliferation.
结论铁合金颗粒使成骨细胞OPG基因表达下降,使破骨细胞分化、活化功能增强,这可能是导致假体松动的骨溶解机制之一。
Conclusion Titanium alloy particles decrease expression of OPG gene in human osteoblasts, and this may contribute to the differentiation of osteoclasts which may lead to the periprosthetic osteolysis.
成骨细胞瘤恰是椎骨上的大骨样骨瘤。
An osteoblastoma is just a big osteoid osteoma in the vertebra.
骨板连续均一,偶尔可见包含骨细胞的腔隙。
The bony spicules are even, with occasional lacunae containing osteocytes.
骨板连续均一,偶尔可见包含骨细胞的腔隙。
The bony spicules are even, with occasional lacunae containing osteocytes.
选用摘除双侧卵巢的山羊颅盖骨,体外分离培养成骨细胞,并对分离的成骨细胞做多方面生物学特性鉴定。
Osteoblasts were isolated from the frontal parietal bone of ovariectomized goat and were confirmed by testing for multiple biological features.
因为骨钙素仅由造骨细胞产生但是却对远在胰腺的细胞起作用。
Because osteocalcin is produced only by osteoblasts yet ACTS on cells far away in the pancreas.
目的从骨髓细胞分化角度研究年龄相关的成骨和破骨细胞分化的机理,探讨老年性骨质疏松症的发生机理。
Objective To discuss the mechanism of age-related the osteoblast and osteoclast differentiation from marrow cells and discuss the mechanism of aged bone loosing disease.
第2周见大量的活跃的成骨细胞、成纤维细胞和间充质细胞,形成骨样组织,软骨细胞增生活跃。
Plenty of active osteoblasts, fibroblasts and mesenchymal cells were seen at the 2nd week, osteoid tissue formed, the proliferation of cartilage was active.
结论接骨中药提取物植入颅骨缺损部位后能促进间充质细胞向成骨细胞分化,从而加速骨缺损的愈合。
Conclusion Local implantation of bone-healing herb extract into skull defect can enhance differentiation of mesenchymal cells to osteoblasts the healing process of bone defects.
结论:淫羊藿苷促进成骨细胞增殖的同时,增强了成骨细胞成骨活性。
Conclusion: the icariin could improve osteoblastic proliferation and develop the osteoblastic activity.
最主要的两个成骨细胞移植来源是椎板和髂嵴,然而,尚未见对这些部位的成骨细胞增殖以及成骨表型的比较研究。
Two common sources of graft are vertebral lamina and iliac crest, however, differences in proliferation and osteoblastic phenotype expression between cells from these sites have not been investigated.
目的:研究成骨生长肽OGP在体外对大鼠颅盖骨成骨细胞I型胶原蛋白的影响。
Objective:To elucidate the effect of osteogenic growth peptide(OGP) on the collagen I in cultured rat osteoblast-like cells.
结论:孕酮对离体胎鼠头盖骨成骨细胞的分化具有多重促进效果,但对细胞的增殖无影响。
Conclusion: Progesterone has a multi stimulating effect on the differentiation of fetal rat calvarial osteoblast, but no effect on cell proliferation.
当骨细胞凋亡率增加,可致骨小梁间空隙加大和骨量减少。
Bone cell apoptosis increases the Spaces of bone trabeculae and decreases the bone mass.
而成骨细胞分化过程受到骨基质中一系列激素和因子的精确调控。
The osteoblast differentiation process is precisely controlled by a series of hormone and genes in the bone matrix.
而成骨细胞分化过程受到骨基质中一系列激素和因子的精确调控。
The osteoblast differentiation process is precisely controlled by a series of hormone and genes in the bone matrix.
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