如今发现了很多种类的骨生长因子，并且取得了重大的研究成果。
Nowadays, many kinds of growth factors in fracture healing have been discovered and the great achievements have been got.
自体骨髓移植可补充成骨基质、骨生长因子和骨祖细胞，有促进骨折愈合的作用。
The autologous bone-marrow grafting improve fracture healing with the supplement of bone matrix, osteoblast.
实验室研究已经证实成纤维细胞的成骨潜能，而多种骨生长因子的联合应用具有更好的促进成骨效果。
Research in the laboratory has proved the fibroblastic potency of bone formation, while the combined applying of many bone growth factors would has much better effects in promoting the bone formation.
目的：观察雌激素对骨折愈合过程超微结构变化和骨生长因子骨形态发生蛋白4基因表达及定位分布的影响。
OBJECTIVE to probe into the effect of estrogen on bone microstructure and bone morphogenetic protein-4 mRNA expression and location during fracture healing.
这一技术应用前景广阔，包括可控性药物和生长因子释放，用于创伤修复，骨组织再生和其他医学应用。
The technology could have several future applications, including controlled release of drugs and growth factors, which are used in wound healing, bone regeneration and other medical applications.
生长因子控制细胞行为并能促进骨移植物与周围骨组织的融合。
Growth factors control cell behavior and are used to help bone grafts integrate with surrounding bone tissue.
目的：富含血小板血浆中含有较高浓度的生长因子，对骨的再生和修复都有一定的促进作用。
AIM: There are growth factors in a high concentration in the platelet-rich plasma, which can improve bone regeneration and repair.
一个理想的骨移植替代材料必须提供骨传导支架、骨诱导性生长因子及具有成骨活性的祖细胞。
An ideal bone-graft substitute must provide scaffolding for osteoconduction, growth factors for osteoinduction, and progenitor cells for osteogenesis.
本文概述近年来在生长因子、基因治疗以及组织工程三方面进展对骨创伤后组织修复基础研究和临床治疗的促进作用。
In this paper, some advances, such as engineered growth factors, gene therapy and tissue engineering, and their application in orthopedic trauma repair and related fields are summarized.
许多研究证实，胰岛素通过过度表达的成骨蛋白-被称为胰岛素样生长因子1（IGF-1）促进骨生长。
Several studies have found that insulin promotes the growth of bone through the over-expression of a bone-building protein known as insulin-like growth factor 1 (IGF-1).
基因治疗被认为是维持骨缺损局部生长因子有效治疗浓度最有希望的一种方法。
Gene therapy is considered to maintain bone defect an effective therapeutic concentrations of local growth factor in the most promising methods.
重组人酸性成纤维细胞生长因子和纤维蛋白载体再生骨。
Recombinant human acidic fibroblast growth factor and fibrin carrier regenerates bone.
其影响因素为局部骨组织、应力、生长因子、上皮细胞、病理环境等。
The influential factors included local bone tissue, stress, growing factor, epithelial cells, pathology surroundings and so on.
结论：骨髓基质细胞-藻酸钙-生长因子复合材料能形成软骨及骨组织。
CONCLUSION: The compound composed of calcium alginate, BMSCs and growth factor might form bone and cartilaginous tissue.
目的观察2型糖尿病患者血糖控制前后对部分骨代谢指标、胰岛素样生长因子- 1 (IGF - 1)及骨密度的影响。
Objective to Observe the influence of partially bone metabolic index, insulin shape growth factor-1 (IGF-1) and bone density for2 type diabetic controls blood sugar before and after.
目的探讨碱性成纤维细胞生长因子对成骨细胞合成骨作用的影响。
Objective To study the effects of basic fibroblast growth factor on bone formation.
膜的组分中，还可包括纳米级骨磷灰石、无机抗菌剂、组织生长因子，缓释药物等。
Osteolith in nano level, inorganic antimicrobial agent, tissue growth factor, and sustained-release drug can be included in the component of the membrane.
目的：观察下颌骨骨缺损愈合过程中骨痂组织内血管内皮细胞生长因子（VEGF）的表达，进一步探讨VEGF对骨缺损愈合的影响。
Objective: To observe the expression of vascular endothelial growth factor(VEGF) in callus during mandibular defect healing and explore the influence of VEGF on defect healing.
比较骨形态发生蛋白2 (BMP - 2)基因治疗与生长因子缓释方法修复节段性骨缺损效果。
To compare the effects between gene therapy and gradual release carrier for bone morphogenetic protein-2 (BMP-2) in repairing bone defects.
结论：碱性成纤维细胞生长因子有诱导成骨作用及诱导血管的形成。
Conclusion: bFGF has the functions of inducing the bone formation and the vascularization.
而在体外研究中碱性成纤维细胞生长因子具有抑制软骨和骨分化的作用。
Basic fibroblast growth factor (bFGF) demonstrate inhibitory effect of bFGF on cartilage and bone differentiation in vitro.
目的探讨血小板衍生生长因子(PDGF) -BB在成骨细胞-破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Objective to investigate the biological effects of platelet-derived growth factor (PDGF) -bb on the osteoclasts in the osteoblast-osteoclast co-culture system.
选择文章内容与血管内皮生长因子和骨缺损修复相关，同一领域文献则选择近期发表或发表在权威杂志文章。
The documents that associated with VEGF and bone defect repair were selected, and those published recently or in authoritative journals were preferred in the same field.
结论：血管内皮生长因子基因转染可促进骨髓基质细胞的成骨分化。
CONCLUSION: Transfection with VEGF 165 gene can promote the osteogenic differentiation of cultured MSCs.
结论：血管内皮生长因子基因转染可促进骨髓基质细胞的成骨分化。
CONCLUSION: Transfection with VEGF 165 gene can promote the osteogenic differentiation of cultured MSCs.
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