然而，最新的检测报道发现在很大一部分骨旁骨肉瘤中有GNAS突变，对该基因突变的特异性提出了质疑。
However, the recent report of GNAS mutations being detected in a significant proportion of parosteal osteosarcoma challenges the specificity of this mutation.
因此我们的研究与先前的研究一致，GNAS的突变在纤维性结构不良中有高度特异性，而在骨旁骨肉瘤和其它低级别骨肉瘤中即使有GNAS突变、也是很少的。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.
因此我们的研究与先前的研究一致，GNAS的突变在纤维性结构不良中有高度特异性，而在骨旁骨肉瘤和其它低级别骨肉瘤中即使有GNAS突变、也是很少的。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.
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