讨论:药物难治性的颞叶癫痫症或潜在疾病是语言延迟发育显著的高危因素。
DISCUSSION: Pharmacologically intractable epilepsy of the temporal lobe, or the underlying condition, is a significant risk factor for delayed language development.
方法颞叶顽固性癫痫24例,手术采用改良翼点入路切口,运用良好的显微外科技术,将癫痫灶切除。
Methods 24 patients with intractable temporal lobe epilepsy were operated via modified pterional approach with good microsurgical technique and the epileptogenic focuses were removed.
结论:颞叶癫痫大鼠海马gad67蛋白表达的增高是癫痫发生后机体的内源性抗痫机制之一。
CONCLUSION: the up-regulation of the expression of hippocampal GAD67 protein in rats with temporal lobe epilepsy is one of the mechanisms of organic endogenous anti-epilepsy after seizures.
目的探讨儿童难治性颞叶癫痫(TLE)术前评估和手术的方法及影响癫痫预后的因素。
Objectives to study the preoperative evaluation, surgical treatment strategies, and factors associated with seizure outcome of refractory temporal lobe epilepsy (TLE) in children.
癫痫特别是难治性癫痫的发病机制尚不完全清楚,而难治性癫痫中颞叶癫痫占据相当大的比例。
Refractory epilepsy in particular, the pathogenesis of epilepsy is not fully understood, and intractable epilepsy of temporal lobe epilepsy occupy a large proportion.
结果难治性颞叶癫痫患者颞叶组织胶质细胞呈不同程度增生,部分有噬神经元现象和神经元变性。
Results Gliosis was observed, to different extent, in the brain tissues from patients with refractory temporal lobe epilepsy, so were neuronophagia phenomenon and neuronal degeneration.
结论难治性癫痫,尤其是内侧颞叶癫痫与人类疱疹病毒- 6感染具有明确的相关性。
ConclusionIntractable epilepsy, especially mesial temporal lobe epilepsy has a close relation ship to human herpesvirus-6.
结果12 7例颞叶癫痫患儿中,9例(7.1% )海马有萎缩性改变,且在T2加权成像和液体率减恢复(FLAIR)成像上呈高信号。
Results Of 127 patients, 9 (7.1%) cases had hippocampal atrophy and showed hyperintense on T2-weighted and fluid-attenuated inversion recovery imaging (FLAIR).
结果12 7例颞叶癫痫患儿中,9例(7.1% )海马有萎缩性改变,且在T2加权成像和液体率减恢复(FLAIR)成像上呈高信号。
Results Of 127 patients, 9 (7.1%) cases had hippocampal atrophy and showed hyperintense on T2-weighted and fluid-attenuated inversion recovery imaging (FLAIR).
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