目的:综述热敏脂质体的原理和它作为靶向药物载体的应用。
OBJECTIVE: The principle of thermosensitive liposomes and its application as drug target carriers are reviewed.
磁性微球作为靶向药物载体有利于提高药物疗效,降低药物的毒副作用,为化疗药物的临床应用开辟了新途径。
The magnetic microspheres may be an alternative of cancer cure, with better anticancer efficacy and less side effects as vehicles for the targeting drug agent.
介绍了用于口服结肠靶向药物载体的几种常见天然多糖,并对以多糖为载体的结肠靶向递药系统进行了概括和分析。
The natural polysaccharides usually used as oral colon-specific drug carrier are introduced. In addition, the colon-specific drug delivery systems with polysaccharides as carrier ar...
通过大量文献,从靶向治疗设计模式、靶向制剂的分类、抗癌靶向药物载体及影响药物靶向性的因素等方面进行探讨。
The models of drug targeting, the categories of drug targeting, the targeted drug carriers, and the factors that influence the effect of targeting are introuduced through domestic literatures.
目的选择一种最佳铁碳复合磁性材料作为药物载体,用于肿瘤的磁靶向治疗。
Objective To select the best magnetic iron-carbon composite microparticles as a drug carrier in magnetically targeted therapy of tumor.
脂质体作为溶栓药物载体,经RGDS修饰后,具有较好的靶向性抗血栓作用。
The results show liposomes as the carrier of medicine has better target anti-thrombus effect after RGDS modifies it.
结论:肝癌特异性多柔比星免疫磷脂纳米粒,有可能成为一种新的药物靶向载体系统。
Conclusion: Doxorubicin phospholipid nanoparticle is able to become a new drug targeting carrier system.
本发明公开了一种叶酸受体靶向脂质体药物载体及其制备方法和应用。
The present invention discloses one kind of folic acid acceptor targeting liposome as medicine carrier and its preparation process and application.
采用新型药物载体使天然药物具有靶向作用是近年来药剂学的研究热点之一。
The research on target drug systems of natural drugs is one of the highlights of pharmaceutics recently.
本文就近年来靶向给药系统作为药物载体的研究及其在临床治疗中的应用进行综述。
The Paper reviews the application and progress of targeted drugs delivery system as drug carriers in clinical therapy.
SLN可以作为治疗肝脏疾病药物的良好肝靶向载体。
SLN is a good liver-targeted drug delivery system for the drug of treating liver disease.
理想的纳米粒载体应有特异靶向性、药物释放可控性,无毒性以及可生物降解等。
The perfect nanoparticle vectors should be specific-targeting, controlled release, nontoxicity? biodegradation, and so on.
温敏在体凝胶作为一种智能水凝胶,可用作药物缓、控释和靶向输送的有效载体。
Temperature-sensitive in situ gel, a kind of smart hydrogel, could be used as a good carrier for sustained, controlled and targeting drug release.
结论骨靶向药物和载体具备低毒、稳定、趋骨性强等特点,能够直接到达病变部位发挥药效,具有很好的开发前景和临床应用价值。
Conclusion Bone-targeting drugs and carriers with low toxicity, high stability and strong bone affinity are valuable to be exploited and applied.
综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。
This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.
免疫毒素是近年来新兴的一种特异性靶向治疗药物,由毒素蛋白和载体两部分构成。
Immunotoxin is a novel class of targeted agents in recent years, which is composed of toxin fragment and antibody or cytokine.
生物可降解型高分子载体控制释放药物和生物可降解型高分子载体靶向药物是近年来高分子药物研究的重点。
Biodegradable macromolecule carried controlled drug releasing and biodegradable macromolecule carried targeted drug delivery are the focus of recent investigation in macromolecular medicine.
聚合胶束作为抗癌药的载体具有靶向作用,可减少毒副作用,提高抗癌药物的化疗指数。
Polymeric micelles used as anticancer drug carriers show a few advantages in the improvement of drug-targeted release and chemotherapeutic efficacy, and the reduction of toxic effects of doxorubicin.
结论:采用磁流体作为药物的载体,在外磁场作用下可实现靶向控制,提高药物在靶部位的聚集浓度。
Conclusion: Ferrofluids as drug carriers can enhance drug concentration in the target with the aid of magnetic field.
该文综述了磁性纳米微粒的现状及其在磁性靶向药物传递中作为药物载体在肝癌治疗中的应用研究进展。
This article summarizes the current state of nano drug carrier with magnetic targeting and the progress as a targeting carrier in the treatment of hepatocellular carcinoma.
脂质体由于具有高度安全性、生物相容性、广泛的载药性等特点,是极具研发前景的靶向、缓释药物载体。
Liposomes are promising drug targeting and controlled release systems, because of their good safety, biocompatibility and drug loading capability.
构建一种药物载体使其能顺利穿透细胞膜并在靶向部位释放,已成为药物设计中亟需解决的问题之一。
To design a new drug vector for promoting the agents across cellular membrane and releasing at the target issues is a persistent challenge.
结论N -琥珀酰壳聚糖样本6与肺癌细胞亲和性强,可作为靶向抗肺癌药物的载体。
CONCLUSION The N-succinyl-chitosan sample 6 has strong affinity to lung cancer cells, and can be used as a kind of drug targeting carrier to lung cancer.
以脂蛋白和载脂蛋白为主要成分构成的脂质体已成为运载抗病毒和抗肿瘤药物受体的靶向性载体。
The liposome made up of apolipoproteins and phospholipid has became a potential carrier for anti-tumor and anti-virus drugs.
目前在药物靶向性给药系统中,脂质体是最成熟和最先进的药物载体之一。
Among several drug delivery systems, liposomal encapsulated anticancer agents represent an advanced and versatile technology.
将具有特殊生理功能的多肽作为基因或药物载体、或用于药物修饰等,可以提高基因转染效率,增强药物的靶向治疗效果,降低药物的毒副作用。
Due to the specific bioactivity of peptides, peptide-based gene and drug delivery systems could achieve improved gene transfection efficiency, enhanced drug targeting property and reduced side-effect.
脂质体作为药物载体,由于其具有靶向性、可降低药物毒性等优点而备受关注。
As a new kind of drug carries, liposomes have been widely studied for their benefits of selectivity and low toxicity.
脂质体作为药物载体,由于其具有靶向性、可降低药物毒性等优点而备受关注。
As a new kind of drug carries, liposomes have been widely studied for their benefits of selectivity and low toxicity.
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