这些药物可能是传统的化疗药物或新型靶向分子药剂。
These drugs may be traditional chemotherapeutic agents or some of the newer molecular targeting agents.
最近,新的靶向分子得到了确认,针对肝癌治疗的多种靶向因子正处于研究中。
Recently, new molecular targets have been confirmed and various targeted agents are now being investigated for the treatment of HCC.
本文着重评述了近年来不同结构类型的DNA靶向分子与DNA相互作用研究方面的进展。
In this article, recent advances in the studies of interactions between DNA and DNA targeting molecules with different structures are reviewed.
方法:综述DNA与其靶向分子的作用方式以及DNA为作用靶的生物活性筛选系统跟踪分离天然植物药活性成分的情况。
METHODS: Review interaction styles of DNA with DNA targeting molecules and bioassay guided isolation of active principles from natural medicinal plants.
png研究人员还发现,抗癌蛋白TRAIL可以作为靶向分子直接绑定到癌细胞的表面,这一点在之前还没有被证明。
The researchers also found that an anticancer protein, TRAIL, can serve as an active targeting molecule to bind directly to the surface of cancer cells, which had not been demonstrated previously.
研究人员认为这个理论已经得到充分的证明,其他的肿瘤细胞只需要利用不同的靶向分子,只不过研究还处在初级阶段而已。
Rozhkova said that a proof of concept is demonstrated, and other cancers can be treated as well using different targeting molecules, but research is in the early stages.
Lapatinib是一种分子药物市场蓬勃发展的产品——被设计用来靶向治疗与疾病相关的特定的蛋白质分子。
Lapatinib is a product of the growing field of molecular medicine-the design of drugs to attack specific protein molecules associated with particular diseases.
此外,极光激酶还参与了肿瘤形成的过程,已经发现一些靶向作用于极光的小分子具有显著的抑癌作用。
Moreover, aurora kinases also function in tumorigenesis. Some small molecules targeting to aurora kinases were found to have significant roles in tumor inhibition.
虽然IPA - 3本身可能不适合人类使用的药物,但这种分子可以形成一个新的靶向治疗的理论基础。
While IPA-3 itself might not be a suitable as a drug for use in humans, the molecule could form the conceptual basis of a new targeted therapeutic.
首先,研究人员不知道人类成血干细胞同样的分子是否刚好是治疗的靶向细胞。
First, the researchers don't know whether the same molecule on human blood-forming stem cells would be the right one to target with a therapy.
现在急切需要靶向不同类型卵巢癌独特的分子缺陷的新药物,虽然这些分子缺陷并非精确地出现在某一类型的癌症中,但有几种还是与之相关。
New drugs are badly needed that can target the distinct molecular defects in the different types of ovarian cancer, which may be more accurately seen as not one disease, but several related ones.
这方面的进展代表着在这个复杂疾病处理上的一个突破。肝癌具有多药耐药性,但研究证明这种分子靶向对其治疗是有效的。
This advancement represents a breakthrough in the management of this complex disease, and proves that molecular targeted therapies can be effective in this otherwise chemo-resistant tumor.
目的端粒酶在多种肿瘤细胞中高表达,可能是肿瘤分子靶向治疗的一个理想靶点。
Aim Telomerase is highly expression in most tumor cells, and it is an ideal target for cancer molecular targeting therapy.
深入研究肿瘤血管异质性分子对于肿瘤诊断、血管靶向治疗等具有重要意义。
And it is significant for the diagnosis of tumors and the therapy targeting tumor vasculatures to research the heterogeneous molecules further.
我们现在正利用蜂毒素分子的无毒性部位将其他药物、靶向药物、或者成像药物与纳米微粒结合起来。
We are now using a nontoxic part of the melittin molecule to hook other drugs, targeting agents, or imaging compounds onto nanoparticles.
分子靶向治疗比传统的化疗特异性强、毒副反应小,将成为今后肿瘤治疗的新趋势。
Molecular targeted therapy has limited or nonexistent side effects on normal cells of the body, unlike traditional chemotherapy.
本文主要对肺癌的分子靶向治疗研究进展进行概括总结。
This article will summarize the new development of molecular targeted therapies currently in lung cancer.
联合使用靶向性氙生物大分子探测器,我们应该可以研究肺中的气体交换,探测最早阶段的癌细胞。
Used in combination with a target-specific xenon biomolecular sensor, we should be able to study the gas-exchange in the lung and detect cancerous cells at their earliest stage of development.
用小分子靶向转录因子以调节特定基因的表达是众所周知难以实现的。
Targeting transcription factors with small molecules to modulate the expression of certain genes has been notoriously difficult to achieve.
研究显示,PDCD4基因在肿瘤治疗中作为一种分子治疗靶向的可能性。
These studies indicated a potential value of PDCD4 as a molecular target in cancer therapy.
分子靶向治疗是近年来肿瘤治疗的一个闪光点,凭着它的特异性和有效性,目前已成为国内外肿瘤治疗的研究热点。
Molecularly targeted therapy is a highlight of new pattern for cancer treatment, which has been a Research hot spot in recent years with its Specificity and Efficacy.
分子靶向治疗是肺癌治疗的新方法。
Molecular targeted therapies are new approaches in lung cancer treatment.
本文针对肝癌的分子靶向治疗的研究进展做一综述。
This review attempts to concisely summarize the molecularly targeted therapy of advanced hepatocellular carcinoma.
目的:鉴定抑制肺癌细胞生长的功能性单克隆抗体1E2及其抗原,为治疗肺癌提供有潜力的靶向抗体治疗剂和分子靶位。
Objective: To identify a functional monoclonal antibody 1E2 against lung cancer and its antigen, so as to provide a candidate antibody drug and molecule target for the anti-lung cancer therapy.
KRAS基因突变在恶性肿瘤组织中频发,可预测非小细胞肺癌分子靶向治疗的疗效和预后,针对RAS基因的分子抑制剂研究仍处于初级阶段。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
这种靶向性的策略包括目的基因对肿瘤细胞的靶向转移,目的基因在肿瘤细胞中的特异表达,以及基因修饰细胞分泌的肿瘤靶向治疗分子。
This can be achieved by tumor targeted gene transfer or tumor specific gene expression, as well as secretion of tumor targeted therapeutic molecules by autologous normal cells.
分子靶向药物I期临床试验:我们更应多注重晚期毒性?
Phase I Trials of Molecularly Targeted Agents: Should We Pay More Attention to Late Toxicities?
靶向超声微泡属于“超声分子影像学”的范畴。
Research on targeted ultrasonic microbubbles belongs to the field of "ultrasonic molecular imaging".
靶向超声微泡属于“超声分子影像学”的范畴。
Research on targeted ultrasonic microbubbles belongs to the field of "ultrasonic molecular imaging".
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