噻唑烷二酮治疗非酒精性脂肪肝炎：继续，停止还是小心前行？
Thiazolidinedione therapy for nonalcoholic steatohepatitis: Go, stop, or proceed with caution?
非酒精性脂肪肝炎(NASH)，是一种与肥胖相关的慢性进展性肝脏疾病。
Nonalcoholic steatohepatitis (NASH) is a chronic progressive liver disease that is strongly associated with obesity.
脂肪性肝病恶化后会很复杂，最严重的是非酒精性脂肪肝炎、肝纤维化、肝硬化。非酒精性脂肪肝会导致肝功能衰竭。
Fatty liver disease can take many forms that vary in severity, with the most severe being nonalcoholic steatohepatitis (NASH), fibrosis and cirrhosis. NAFLD can lead to liver failure.
结果：酒精性脂肪肝、非酒精性脂肪肝患者与健康对照组比较均存在明显的胰岛素抵抗，而肝炎相关性脂肪肝与健康对照比较则不明显。
Results:Compared with nomal subjects, all patients with alcoholic fatty liver and no-alcoholic fatty liver had apparent insulin resistance; however, others that induced by hepatitis virus hadn't IR.
而20%的非酒精性脂肪肝的患者会进展为非酒精性脂肪型肝炎(简称NASH)。
We know that 20% of those nonalcoholic fatty liver disease patients will go on to progress to a condition called NASH, which is nonalcoholic Steatohepatitis.
此外，非酒精性脂肪肝是肝癌的发病率与观察肝炎患者一旦感染C -肝硬化建立。
Furthermore, hepatocellular carcinoma incidence in NAFLD is comparable with that observed in hepatitis C-infected patients once cirrhosis is established.
我们及其他研究者最近得出的这一结论适用于多种肝脏疾病，包括乙型慢性病毒性肝炎、丙型慢性病毒性肝炎、酒精性肝病和非酒精性脂肪肝。
We and others have pointed this out recently for several liver diseases, including chronic viral hepatitis B and c, alcoholic liver disease, and non-alcoholic fatty liver disease.
我们及其他研究者最近得出的这一结论适用于多种肝脏疾病，包括乙型慢性病毒性肝炎、丙型慢性病毒性肝炎、酒精性肝病和非酒精性脂肪肝。
We and others have pointed this out recently for several liver diseases, including chronic viral hepatitis B and c, alcoholic liver disease, and non-alcoholic fatty liver disease.
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