目的:探讨KAI1/CD82 基因在非小细胞肺癌(NSCLC)组织中的表达水平及在癌细胞发生侵袭、转移过程中的意义。
Objective: To study the expression of KAI1/CD82 in non-small cell lung carcinomas (NSCLC) and explore the mechanism of invasion and metastasis of tumor cell.
这些转移性癌细胞比那些非转移性的细胞更加易于迁移,但我们对于迁移如何进行还所知甚少。
These metastatic cells tend to move more than their non-metastatic variants but this movement is poorly understood.
目的:建立原位移植裸鼠模型,筛选同一标本来源的转移性和非转移性肾细胞癌(RCC)。
Objective: to establish orthotopic mouse models of human renal cell carcinoma and to separate metastatic or non-metastatic renal cell carcinoma (RCC) from the same source.
目的探讨非小细胞肺癌伴单发脑转移瘤的外科治疗及预后。
Objective To investigate the clinical value of surgical treatment and prognosis for non-small cell lung with isolated cerebral metastasis.
检测CD44蛋白和基因的表达,可能对判断非小细胞肺癌病人的预后、预测淋巴结的转移趋势,具有重要的临床意义。
CD44 expressions may have significant clinical importance in the evaluation of the patient prognosis and the potential tendency of lymph nodes metastasis.
目的研究CD 44蛋白在人非小细胞肺癌组织中的表达及其与非小细胞肺癌淋巴转移的关系。
Objective To investigate the correlation between expression of CD44 in human non-small cell lung cancer and lymph node metastasis.
目的:确定立体定向放射外科治疗非小细胞肺癌单发脑转移瘤是否需合并全脑照射。
Objective To determine if the whole brain radiotherapy (WBRT) is necessary in patients with single brain metastases from non small cell lung cancer treated with stereotactic radiosurgery (SRS).
目的探讨非小细胞肺癌同一肺叶内转移的外科治疗效果并评估其TNM分期。
Objective: We evaluated the surgical results and TNM classification of the non-small-cell lung cancer with intrapulmonary metastasis in the same lobe as the primary.
背景与目的脑转移已经成为局部晚期非小细胞肺癌(NSCLC)治疗失败的最主要因素之一。
Background and objective Brain metastasis has become one of the most important factors of the failure of treatment of locally advanced non-small cell lung cancer (LANSCLC).
非转移性乳腺癌细胞依靠与其他细胞和细胞外基质相互作用而生存。
Non-metastatic breast cancer cells rely on interactions with other cells and the extracellular matrix to survive.
目的探讨血管内皮生长因子(VEGF)含量对非小细胞肺癌(NSCLC)血道转移的影响。
Objective To evaluate the effect of vascular endothelia1 growth factor(VEGF)on the hematogenous metastasis of non small cell lung cancer (NSCLC).
目的探讨手术治疗在非小细胞肺癌(NSCLC)单发脑转移综合治疗中的作用。
Objective To investigate the role of surgical resection in comprehensive treatment for patients with non-small cell lung cancer (NSCLC) and solitary brain metastasis.
结论:血清mmp2和MMP9浓度可作为预测非小细胞肺癌转移的指标。
Conclusions: Serum total MMP 2, MMP 9 levels may provide prognostic information of NSCLC metastasis.
结论:CD44 V 6阳性表达预示非小细胞肺癌具有较强的侵袭和转移能力,CD 44 V 6可作为一项预测非小细胞肺癌转移潜能及判断预后的生物学指标。
Conclusion: CD44V6 positive expression indicated that NSCLC has stronger invasion and metastasis potential. CD44V6 is a useful marker of predicting the metastatic potential and the prognosis of NSCLC.
目的探讨常规应用纵隔镜检查周围型T1N0M0非小细胞肺癌纵隔淋巴结转移情况。
Objective To evaluate routine mediastinoscopy in detecting mediastinal lymph nodes status in patients with peripheral T1N0M0 non-small cell lung cancer (NSCLC).
方法:用免疫组化技术检测了52例非小细胞肺癌及转移淋巴结中ICAM-1的表达。
Methods:ICAM 1 Expression in 52 cases of primary and metastatic NSCLC were studies on cytostat sections by means of immunohistochemistry.
目的研究蛋白激酶C(PKC)、粘附分子CD44变构体CD44V3-10在非小细胞性肺癌(NSCLC)中定量表达及在肺癌发生及转移中的作用。
To investigate the quantitative expression and roles of protein kinase C (PKC), Variant CD44 (CD44V3-10) adhesion molecules in Non-small cellular lung cancer (NSCLC).
这是一例转移性非小细胞肺癌。
PTEN蛋白的表达水平可作为判断非小细胞肺癌分化、淋巴结转移及预后的分子生物学指标。
The expression of PTEN protein can be a good molecular biological indicator for determining differentiation degree, lymph node metastasis, and prognosis of NSCLC patients.
目的比较非小细胞肺癌骨转移的综合治疗与单一方法治疗的效果。
Objective To compare the therapeutic effects of single- and combined-modality therapy on bone metastasis of non-small-cell lung cancer.
井上说:“这是一个理想的个体化治疗转移性非小细胞肺癌的开始。”
"This is a beginning of the ideal individualized treatment for metastatic non-small-cell lung cancer," said Inoue.
目的:观察非小细胞肺癌脑转移患者综合治疗疗效及毒副反应。
Objective: To analyse the effect and side-effect of comprehensive therapy on patients in non-small cell lung cancer with brain metastasis.
用功能基因组学、分子流行病学和生物信息学等手段,研究非小细胞肺癌的转移机理、脑胶质瘤的发生机理。
Using functional genomics, molecular epidemiology, bioinformatics and other approaches to study the metastasis mechanism of NSCLC, and carcinogenesis of glioma.
随着小分子酪氨酸激酶抑制剂在非小细胞肺癌治疗上获得成功,陆续有其治疗非小细胞肺癌脑转移及脑膜转移的研究。
With the success of small-molecule tyrosine kinase inhibitors in non-small cell lung cancer, recent clinical researches have shown their activities against brain and leptomeningeal metastases.
研究发现MTA1蛋白的高表达与非小细胞肺癌的淋巴结转移密切相关,它可以作为一个预测非小细胞肺癌淋巴结转移和判断预后的指标。
The expression level of MTA1 protein is related to the lymph node metastasis in NSCLC, which would become a signal for predicting lymph node metastasis and prognosis in NSCLC.
本文就小分子酪氨酸激酶抑制剂治疗非小细胞肺癌脑转移的机理、临床应用以及治疗失败后的处理等方面作一综述。
The mechanisms, clinical applications of small-molecule tyrosine kinase inhibitors on brain metastasis and therapeutic choice after the failure will be reviewed in this article.
结论:同步放化疗治疗局部晚期非小细胞肺癌具有较好的疗效,不良反应可耐受,治疗失败原因主要为远处转移。
Conclusions: Concurrent radiochemotherapy is a feasible, well tolerated and active scheme in the treatment of locally advanced NSCLC. The major pattern of failure is distant metastasis.
针对脑转移瘤的ALK重排的非小细胞肺癌。
Targeting brain metastases in ALK-rearranged non-small-cell lung cancer.
目的对75岁以上无远处转移非小细胞肺癌患者单纯放疗和联合放、化疗的疗效进行回顾性分析。
Objective To evaluate the effect between radiotherapy alone and combined radio chemotherapy on more than 75 year old patients with m 0 NSCLC by retrospective analysis.
目的对75岁以上无远处转移非小细胞肺癌患者单纯放疗和联合放、化疗的疗效进行回顾性分析。
Objective To evaluate the effect between radiotherapy alone and combined radio chemotherapy on more than 75 year old patients with m 0 NSCLC by retrospective analysis.
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