目的：在人类基因组中，有98%的DNA序列属于非编码序列。
Objectives: 98% of DNA sequence in human genome belongs to non-coding sequence.
合理建模非编码序列对正确识别DNA序列中的调控元件非常重要。
Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences.
非编码序列，特别是内含子的起源，是一个重要的悬而未决的问题。
The origin of non-coding sequences, especially introns, is an outstanding issue that has been receiving continuous debate for the last two decades.
核苷酸替换偏好性受其相邻碱基组成的影响现象已经在核基因组假基因序列和叶绿体基因组的非编码序列和编码序列中发现。
Influence of neighboring base composition on nucleotide substitution bias was observed in the sequence of nuclear pseudogenes and chloroplast non-coding and coding sequences.
比较基因组学的研究发现： 人类基因组中约5%的序列受到选择压力的限制， 但编码序列只占其中很小一部分， 约3.5%是保守、非编码序列。
Study of comparative genomics has revealed that about 5% of the human genome are under purifying selection, 3.5% of which are conserved non-coding elements (CNEs).
比较基因组学的研究发现： 人类基因组中约5%的序列受到选择压力的限制， 但编码序列只占其中很小一部分， 约3.5%是保守、非编码序列。
Study of comparative genomics has revealed that about 5% of the human genome are under purifying selection, 3.5% of which are conserved non-coding elements (CNEs).
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