目的探讨母系遗传性非综合征性耳聋的听力学特征及分子遗传学机制。

Objective To explore audiological features of matrilineal non syndromic deafness and its molecular mechanism.

youdao

结论GJB2突变是导致学语前聋的主要原因，28.6%的学语前隐性和18.9%学语前散发非综合征性耳聋病人携带了两个GJB2突变。

Conclusion the mutations in GJB2 are the major cause of prelingual deafness; two causative mutations can be found in (28.6%) prelingual recessive and in (18.9%) prelingual sporadic NSHL patients.

youdao

结论GJB2突变是导致学语前聋的主要原因，28.6%的学语前隐性和18.9%学语前散发非综合征性耳聋病人携带了两个GJB2突变。

Conclusion the mutations in GJB2 are the major cause of prelingual deafness; two causative mutations can be found in (28.6%) prelingual recessive and in (18.9%) prelingual sporadic NSHL patients.

youdao