近年来，非病毒载体的研究越来越受到重视。
Recently, researchers pay more and more attention to non-viral vector.
因此寻找新的非病毒载体成为目前的研究热点。
The recent topic has been focused on the new non-viral vectors.
基因转移载体是基因治疗的重要组成部分，包括病毒载体和非病毒载体。
Gene transfer vector is the important ingredient in gene therapy, which includes virus vector and non-virus vector.
本发明还涉及此复合药物及单独的非病毒载体在恶性肿瘤治疗中的用途。
The invention also relates to application of the composite medicine and the independent non-viral vector in the treatment of the malignant tumor.
基因转移载体是基因治疗的重要组成部分，包括病毒载体和非病毒载体。
Gene transfer vector is the important ingredient in gene therapy, which includes virus vector and nan-vires vector.
本发明还涉及包含所述非病毒载体和所述表达型重组体的药物组合物及其应用。
The invention also relates to the pharmaceutical compositions containing the non-viral vectors and the expression type recombinant and their use.
壳聚糖作为一种天然生物多糖物质，已被证明是具有潜在前景的非病毒载体材料。
Chitosan is the natural biological polysaccharide which has been proven to be the potentially promising non-viral vector materials.
结论LPD是一种制备工艺简单、体外稳定性好、转染率高，具有应用潜力的非病毒载体系统。
Conclusion LPD could be prepared easily with small particle sizes and high transfection activities. LPD may be good non-viral vectors for applications in gene delivery.
目的研究新型非病毒载体磷酸钙纳米颗粒的生物学特性，评估其在肿瘤基因治疗中应用的前景。
ObjectiveTo study the biological characteristics of calcium phosphate nanoparticles and evaluate the promising in cancer gene therapy.
近年来，许多阳离子脂质体、阳离子多肽及阳离子聚合物被用作非病毒类的基因输送载体。
In recent years, many kinds of cationic lipids, oligopeptides and polymers have been developed as non-viral gene delivery materials.
默克疫苗的失败至多代表非复制型腺病毒载体疫苗的失败，决不代表其他艾滋病疫苗就没有希望。
The failure of the Merck vaccine up on behalf of the non-replicating adenovirus vector vaccine failure, not on behalf of other AIDS vaccines will be no hope.
聚氨基酸材料由于可生物降解性，低毒性等特点而被广泛的作为非病毒性基因载体材料的研究。
Polyaminoacid materials are widely researched as non-viral gene vectors because of the advantages, such as biodegradation, low cytotoxicity and so on.
无机纳米颗粒类非病毒型基因载体因其稳定性好、生物亲和性好、安全、有效、无免疫原性等优点，已引起广泛关注。
Inorganic nanoparticles as non-viral gene carriers have caught much attention because of their good stability, biocompatibility, safety, efficiency and non-immunogenicity.
非病毒的基因载体比病毒性基因载体具有高安全性、低免疫原性及易于生产的特点。
Nonviral gene vectors have many inherent advantages over viral vectors in terms of safety , immunogenicity and ease of manufacture.
非病毒基因载体主要有脂质体、人工合成聚合物载体、天然聚合物载体、局部基因释放载体等。
Nonviral gene carriers include liposomes, synthetic polymeric vectors, natural polymeric vectors, local gene delivery vectors and so on.
非病毒基因载体主要有脂质体、人工合成聚合物载体、天然聚合物载体、局部基因释放载体等。
Nonviral gene carriers include liposomes, synthetic polymeric vectors, natural polymeric vectors, local gene delivery vectors and so on.
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