另外还发现三倍体及非整倍体细胞的存在。
In addition, triploid and aneuploid cells were also observed in some variants.
羊膜穿刺术是出生前检测非整倍体的金标准。
Amniocentesis is the standard prenatal detection procedure for aneuploidy.
本发明属于小麦非整倍体生物技术育种领域。
The invention belongs to the field of wheat aneuploid biotechnics breeding.
非整倍体与肿瘤相关。
未发现有非整倍体细胞和染色体形态结构变异。
Aneuploids and chromosomes structure variation were not found.
非整倍体所描述是单倍体数目(n)并非成倍增加。
Aneuploid describes chromosome Numbers which are not multiples of the haploid number (n).
非整倍体异常的非入侵性产前诊断： 离现实有多近?。
Non-invasive prenatal diagnosis of aneuploidies: how close to reality?
在过去几年中，科学家利用小鼠研究了非整倍体的遗传原因。
For the past several years, scientists have used mice to study the genetic causes of aneuploidy.
他们发现具有高水平非整倍体的肿瘤患者在治疗后没有活多久。
They saw that patients whose tumours had high levels of aneuploidy didn't live for as long after treatment.
多数文献报告，在恶性胸腔积液中，细胞染色体可呈非整倍体性。
It's reported in many articles that aneuploids are observed in the chromosomes of malignant pleural effusion cells.
与此同时，单倍体细胞逐渐减少，产生大量多倍体和非整倍体细胞。
Meanwhile the ratio of haploid cell in the callus dropped gradually, and a lot of polyploid and aneuploid cells appeared.
前言：目的：建立采用第一极体植入前染色体非整倍体诊断的方法。
Objective: To establish the method of preimplantation genetic diagnosis (PGD) by use of first polar bodies.
目的建立多色荧光原位杂交技术检测人卵细胞染色体非整倍体的方法。
Objective: To establish the method of aneuploidy detection in human oocytes by multicolor fluorescence in-situ hybridization (M-FISH).
研究人员希望将来他们能够研究出他们称之为“非整倍体疗法”的药物。
The researchers hope that, in the future, they can develop what they are calling "aneuploidy therapy."
早期传代细胞染色体数出现非整倍体和非稳定性畸变，同时有两个标记染色体；
There were aneuploid and instable structure changes in chromosomes, and two marker chromosomes at the same time.
四倍体育种中染色体组操作的结果除了产生整倍体外，还产生大量的非整倍体。
Manipulation of chromosome in tetraploid breeding resulted in not only euploids, but also a great many aneuploids.
研究表明，TBZ可能通过抑制微管蛋白聚合来影响染色体正常分离，诱发非整倍体。
The result suggested that TBZ may induce aneuploidy by the pathway of tubulin polymerization inhibition which is able to lead to chromosomal malsegregation.
除了正常染色体对以外，还存在有第二种同源染色体的非整倍体状态，被称为三体性。
An aneuploid state in which a third homologous chromosome is present in addition to the normal autosomal pair is called trisomy.
尽管非整倍体的发生率高、临床后果严重，但人类对于非整倍体究竟是如何发生的仍然不清楚。
Despite its high incidence and severe clinical consequences, very little is known about how aneuploidy originates in human.
但当哺乳动物为非整倍体时，即每个染色体不再有两个拷贝时，他们通常会长出一个较大的细胞核。
Nevertheless, when mammalian cells become aneuploid - that is, they no longer have two copies of each chromosome - they often grow a larger nucleus.
目前，使用PGD技术，可以测试出许多种不同的疾病，包括非整倍体，单基因病和染色体易位等。
Currently, we are able to perform PGD for many genetic conditions including single gene disorders and chromosome abnormalities.
结果卵圆细胞在培养过程中倍增时间逐渐缩短，非整倍体染色体数目增加，在软琼脂中生长的克隆增多。
Results During long term cultivation, the population doubling time of the cells became shorter and the percentage of aneuploidy chromosomes and colonies grown in soft AGAR increased.
一旦某个异常增生给归类为癌症或肿瘤，也有人将其中细胞的高度非整倍体性，视为癌细胞侵犯性的征兆。
Once an abnormal growth is defined as a cancer, or neoplasm, high cellular aneuploidy is also considered by some to be a sign of aggressiveness.
而对于多倍体生物，如体细胞中每条染色体具有三个或三个以上的拷贝，二体或双体就是一种非整倍体状况。
For organisms that normally have three or more copies of each chromosome (those that are triploid or above), disomy is an aneuploid chromosome complement.
非整倍体是人类生殖生物学中的重要问题，是引起自发性流产和新生儿中多种先天性畸形综合征的主要原因。
Aneuploidy is an important point at issue in human reproductive biology, accounting for both a major proportion of miscarriages and various congenital malformation syndromes among newborns.
方法：我们开发了基于游离DNA定向分析的方法，用于胎儿21号、18号和13号染色体非整倍体的检测。
METHODS: We developed an assay based on the targeted analysis of cell-free DNA for the detection of fetal aneuploidies of chromosomes 21, 18, and 13.
这个新研究表明，DNA数量的错误和它在癌细胞里面如何包装-叫做非整倍体-可能影响免疫系统的能力来毁坏肿瘤细胞。
The new study suggests that errors in the quantity of DNA and how it's packaged inside cancer cells - called aneuploidy - might affect the immune system's ability to destroy the cells.
该药物能够准确的将正确的染色体数目导入每一新细胞，产生非整倍体细胞，能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。
Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.
Cleveland教授实验室的研究者建立染色体数目有明显变异的小鼠模型，并分析该非整倍体小鼠模型是否更容易罹患肿瘤。
To find out, researchers in the Cleveland lab created and analyzed mouse models with cells having a highly variable number of chromosomes to discover if such aneuploidy made the mice more tumor-prone.
结果64%的卵细胞核型正常，36%的卵细胞为非整倍体，其中22%为同源染色体不分离，14%为姐妹染色单体非平衡性过早分离。
Results 64% of oocytes were normal, 36% of oocytes were aneuploidy, of which 22% were due to nondisjunction and 14% unbalanced predivision.
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