结论雷公藤甲素在雷公藤药材中有不稳定现象存在。
CONCLUSION Triptolide content in Radix Tripterygii is not constant during its storage.
目的研究雷公藤甲素对H 22细胞的诱导凋亡作用。
Objective It is to study the inducing H22 cell apoptosis action of triptolide.
ACTH在雷公藤甲素组大鼠垂体中的表达高于空白对照组。
The expression of ACTH in the group of the Triptolide was higher than that of control group.
并对雷公藤甲素外用凝胶进行皮肤刺激性实验和初步药效学考察。
The skin irritation experiments and elementary pharmacodynamics tests of Triptolide gels was conducted.
结果雷公藤甲素在雷公藤药材中的含量随着存贮时间的增长而下降。
RESULT Triptolide content decreased with the increase of time of its storage.
四甲基偶氮唑盐（MTT）法检测雷公藤甲素对细胞增殖的减轻情况；
The MTT colorimetry method was performed to measure the inhibitive effect of triptolide on cell proliferation;
雷公藤甲素外用凝胶对皮肤无明显刺激性，对类风湿性关节炎又一定疗效。
The gels have no skin irritation and have certain effect to inflammation induced by Freund's adjuvant.
目的了解较长期使用雷公藤甲素对正常大鼠血浆促肾上腺皮质激素(ACTH)含量的影响。
ObjectiveTo Study the effect of long-term triptolide use on the content of the normal rat plasma ACTH.
结论较长期服用雷公藤甲素对大鼠肾上腺皮质具有毒性作用，且其毒性作用具有时间节律性。
Conclusion Comparatively chronic use of TP may impose toxicity on the adrenal cortex of rats and the toxic effect appears associated with temporal rhythm.
目的研究雷公藤甲素涂层支架抑制新生内膜增殖的有效性、量效关系，并研究该支架的安全性。
Objective to investigate the effectiveness dose-effect relationships for inhibiting proliferation by Triptolide-eluting stent, and the safety of the Triptolide eluting stent.
本文研究了反相高效液相色谱和超速冷冻离心测定雷公藤甲素聚乳酸纳米粒包封率和载药量的方法。
The encapsulation efficiency and drug loading of triptolide-loaded poly (d, L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study.
利用我们已建立的动物模型观察雷公藤甲素对实验鼠移植皮片存活期、MLR及IL-2水平的影响。
The effects of TRIPTOLIDE(TL) on mouse skin graft survival period, MLR and IL2 level were observed with our established animal model.
方法以甲醇-水为流动相，采用HPLC梯度洗脱法，测定了雷公藤药材的根、枝、叶中雷公藤甲素在不同存贮期的含量。
METHOD HPLC gradient elution method was used with methanol-water as the mobile phase to determine the contents of triptolide in its root, branch and leaf at different periods of its storage.
方法：利用ELISA和免疫组织化学法检测雷公藤甲素和IL-18刺激的滑膜成纤维细胞合成、释放IL-8的水平。
Methods:We use ELISA and Immunohisto-chemistry to observe the level of IL-8 produced and released by SFs stimulated by IL-18 and triptolide.
方法：利用ELISA和免疫组织化学法检测雷公藤甲素和IL-18刺激的滑膜成纤维细胞合成、释放IL-8的水平。
Methods:We use ELISA and Immunohisto-chemistry to observe the level of IL-8 produced and released by SFs stimulated by IL-18 and triptolide.
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