首先，他们用基因手段禁止了细胞受体的活动——细胞受体即那些向其他细胞发送和从其他细胞接受信号的分子们——因为雌激素和雄激素存在于正在发育的老鼠胚胎的肢芽中。
First, they used genetic tools to deactivate cell receptors-molecules that send and receive signals to and from other cells-for testosterone and estrogen in the developing limb buds of mouse embryos.
此外，在ER+/PR+（雌激素受体阳性/孕激素受体阳性）恶性肿瘤和接受阿那曲唑作为内分泌治疗的患者中，发现了（大豆异黄酮和绝经妇女乳腺癌复发率之间）相反的关联。
Additionally, inverse associations were found in those who wee diagnosed with ER+/PR+ malignancy and those who receiving anastrozole as endocrine therapy.
根据这项新的研究，的确，对雌激素受体阳性肿瘤和雌激素受体阴性肿瘤的妇女都有利。
According to this new study, yes, it is beneficial to both women who have estrogen receptor positive tumors and estrogen receptor negative tumors.
雌激素与血管内的受体结合通常可使血管壁保持弹性和处于扩张状态，并与其它心脏保护机制一同修复受损的脉管系统。
The normal result of this estrogen binding is that blood vessel walls remain elastic and dilated, and damage to the vasculature is repaired, among other heart-protective effects.
通过该款应用，乳腺癌患者可输入和跟踪病症及治疗情况的详细信息，比如肿瘤的大小和雌激素受体的有无等。
Using this app, breast-cancer patients enter and track details of their disease and treatment, from the size of the tumor to the presence or absence of estrogen receptors.
结论：染料木黄酮不是通过促进雌激素受体基因和蛋白的表达来促进成骨细胞增殖。
CONCLUTION Genistein promotes the proliferation of osteoblast not through promoting the expression of estrogen receptor gene and protein.
结论：这是第一篇雌激素受体阳性乳腺癌患者使用和不使用三苯氧胺治疗，明确区分17hsd1和17hsd2表达量对预后和预测之间的重要性。
Conclusions: This is the first report that clearly distinguishes between the prognostic and predictive importance of 17hsd1 and 17hsd2 in ER-positive breast cancer treated with or without tamoxifen.
据《自然遗传学》报道，研究人员宣称2号染色体和16号染色体发生基因变异会增加雌激素受体阳性的乳腺癌发病率。
Reporting in Nature Genetics, researchers said genetic variants on chromosome 2 and on chromosome 16 May increase the risk of estrogen-receptor-positive breast cancer.
在异型配子ZW胚胎中，雌激素受体、类固醇生成因子- 1和P 450芳香化酶基因的表达可刺激卵巢的形成。
While in the heterozygotic ZW embryo, expression of estrogen receptor, steroidogenic factor-1 and P450 aromatase might stimulate ovarian formation.
雌激素受体的改变与年龄相关的记忆缺陷和女性阿尔茨海默病有关。
Changes in the estrogen receptor have been associated with age-related memory deficits and an increased incidence of Alzheimer's disease among women.
他们检查了各种雌激素受体彼此之间的关系怎样以及与肿瘤大小、淋巴结侵袭和转移的关系。
They examined how the various estrogen receptors associated with each other and their relationship with size of the primary breast tumor, lymph node invasion, and development of metastasis.
经过很多的研究之后确立了两个因素：雌激素受体表达和增殖能力也就是肿瘤细胞分解的速率。
Two factors were established during numerous studies: estrogen receptor expression and proliferative activity, i. e. , the rate of tumor cell division.
目的：探讨选择性雌激素受体调节剂雷洛昔芬对去卵巢大鼠血压、血脂、纤维蛋白原和雌激素受体的作用。
Objective: To investigate the effect of raloxifene, a selective estrogen receptor modulator, on blood pressure, lipid, fibrinogen and estrogen receptor in ovariectomized rats.
在55例晚期乳癌病人中研究了抗雌激素他莫昔芬（TAM）治疗效果和乳癌雌激素受体（ER）状态的关系。
The objective response to antiestrogen tamoxifen (TAM)in advanced breast cancer with respect to its estrogen receptor (ER) Status was studied in 55 patients.
结果表明，不同发育时期的卵原细胞和卵母细胞中都存在雌激素、雄激素和孕激素受体。
The results indicated that the receptors of estrogen, androgen and progestogen existed in oogonia and oocytes of different developmental stages.
目的：探讨雌激素受体(ER)、孕激素受体(PR)和HOXA - 9基因在人输卵管中的表达及与输卵管妊娠的关系。
Objective: to investigate the expression of estrogen receptor (er), progesterone receptor (pr) and HOXA-9 gene in human fallopian tube and pregnant fallopian.
目的：研究长期雌激素替代治疗对血压及心肌组织胰岛素受体(IR)和胰岛素受体底物1 (IRS 1)表达水平的影响。
Objective to determine the effects of long-term estrogen replacement treatment on blood pressure and expressions of insulin receptor (IR) and insulin receptor substrate-1 (IRS-1) in myocardium.
综述近几年上市或开发中的雌激素受体调节剂类药物，主要包括选择性雌激素受体调节剂和纯抗雌激素药物。
The estrogen receptor modulator drugs launched or developed in recent years were reviewed, mainly including selective estrogen receptor modulators and pure antiestrogen.
三阴性乳腺癌是雌激素受体、孕酮受体和HER2检测皆为阴性的乳腺癌。
Triple-negative breast cancers are breast cancers that have tested negative for estrogen receptors, progesterone receptors and HER2.
摘要：本研究旨在探讨大蒜素对小鼠脾细胞雌激素和雄激素受体的影响。
Abstract: the aim of this study was to observe the effects of allicin on estrogen and androgen receptors of mice spleen cells.
应用兔抗雌二醇抗体、兔抗孕酮抗体，鼠抗雌激素受体和鼠抗孕激素受体抗体来检测乳腺癌等病例。
The antibodies of rabbit anti estradiol and progesterone, the receptor antibodies of estradiol and progesterone were used for detecting the breast cancer cases.
目的克隆人表皮生长因子受体（HER2）基因，建立共表达HER2基因和雌激素受体（ER）基因的MCF-7细胞模型。
Objective To clone human epidermal growth factor receptor (HER2) gene and establish a MCF-7 cell line with stable co-expression of HER2 and estrogen receptor (ER).
方法以体外培养雌激素受体阳性细胞MCF - 7为研究对象，采用MTT法和流式细胞术法检测MCF - 7细胞存活率和细胞凋亡。
Methods MTT assay and flow cytometer (FCM) assay were used to determine the survival rate and apoptosis of MCF-7 cells, which was estrogen receptor positive in culture.
目的观察雌二醇、结合雌激素和雌激素受体调节剂对去卵巢大鼠摄食行为的影响。
ObjectiveTo investigate the effects of the estradiol, conjugated estrogen and raloxifene on the food intake behavior, locomotor activity and sucrose choice in the ovariectomized rats.
选择性雌激素受体调节剂是一类在不同的组织细胞中对雌激素受体发挥不同调节作用的化合物，用于治疗绝经后妇女的骨质疏松和乳腺癌等。
Selective estrogen receptor modulators (SERMs) are kinds of compounds that exert different biological effects on er in different tissues and can be used in the tr.
方法应用实时监测聚合酶链反应检测这三种受体基因在雌激素受体阳性和雌激素受体阴性乳腺癌细胞系中的表达。
Methods These three genes were quantified by real-time quantification polymerase chain reaction (PCR) in er positive and er negative breast cancer cell lines.
结论雌激素水平明显影响雌鼠心脏组织和肺血管内皮细胞中雌激素受体的含量，高脂饮食可明显降低组织和细胞中雌激素受体的含量。
Conclusions the content of er in VEC and hearts are affected by serum estrogen level, and cholesterol rich diet decrease the content of er remarkably.
Pinkerton博士称，在该项研究之前，医生用三苯氧胺治疗和预防雌激素受体阳性乳腺癌。
Prior to this study, tamoxifen was used for the treatment and prevention of oestrogen receptor-positive breast cancers, Dr. Pinkerton said.
有研究表明，这类物质进入人体后可以与雌激素受体结合，影响内分泌，和乳腺癌有关。
Previously published studies have shown that parabens are able to be absorbed through the skin and to bind to the body's estrogen-receptors, where they can encourage breast cancer cell growth.
有研究表明，这类物质进入人体后可以与雌激素受体结合，影响内分泌，和乳腺癌有关。
Previously published studies have shown that parabens are able to be absorbed through the skin and to bind to the body's estrogen-receptors, where they can encourage breast cancer cell growth.
应用推荐