有些患者甚至在治疗后其骨髓中仍然存有aml细胞。这叫做难治性白血病。
Some patients still have AML cells in their marrow even after treatment. This is called refractory leukemia.
对于难治性白血病，可能会用到在AML第一阶段治疗中用不到的药，也可能会进行干细胞移植。
With refractory leukemia, drugs that were not used to treat the patient's AML in the first part of treatment may be given. Stem cell transplantation also may be used.
氯法拉滨注射液适用于对至少2种治疗方案无效的儿童(1 - 21岁)难治性或复发性急性淋巴细胞白血病的治疗。
Clofarabine injection is indicated for the treatment of pediatric patients (ages 1-21 years) with relapsed or refractory acute lymphoblastic leukemia after at least 2 previous regimens.
急性髓细胞性白血病(aml)很难治愈，不过可喜的是近年来疗效已有所改善。
AML is a hard blood cancer to cure. The good news is that there has been improvement in treatment results in recent years.
替匹法尼用一周，停一周剂量递增治疗复发性，难治性或高危髓细胞性白血病1阶段试验。
A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia.
目的观察131I-GMCSF诱导HL60/ADM细胞凋亡，探讨其诱导HL60/ADM细胞凋亡的机制，比较131I-GMCSF对HL60/ADM细胞和HL60细胞的细胞毒作用，为其临床治疗难治性或复发性急性髓细胞性白血病提供实验依据。
Objective: To compare the cytotoxicity of HL60/ADM cells and HL60 cells treated with 131I-GMCSF and to investigate the mechanism of the apoptosis of HL-60/ADM cells induced by 131I-GMCSF.
目的观察131I-GMCSF诱导HL60/ADM细胞凋亡，探讨其诱导HL60/ADM细胞凋亡的机制，比较131I-GMCSF对HL60/ADM细胞和HL60细胞的细胞毒作用，为其临床治疗难治性或复发性急性髓细胞性白血病提供实验依据。
Objective: To compare the cytotoxicity of HL60/ADM cells and HL60 cells treated with 131I-GMCSF and to investigate the mechanism of the apoptosis of HL-60/ADM cells induced by 131I-GMCSF.
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