结论伽玛刀是治疗难治性癫痫的有效方法之一。
Conclusion Gamma knife is one of effective method in treating the intractable epilepsy.
目的：探讨手术对难治性癫痫患者认知功能的影响。
Objective: To investigate the effects of surgery on cognitive functions of patients with intractable epilepsy.
加巴喷丁可以作为小儿难治性癫痫的一种治疗选择。
Gabapentin can, therefore, be a choice for the treatment of refractory epilepsy in children.
本文对难治性癫痫近年来有关多药耐药现象进行综述。
In this paper, the recent progresses about the multi-drug resistance in the treatment of intractable epilepsy were summarized.
目的探讨难治性癫痫致痫灶定位方法和手术治疗效果。
Objective to explore the location methods of epilepsy seizures and effective surgical treatment for refractory epilepsy.
最常见的难治性癫痫综合症是复杂性部分发作型癫痫。
The most common epileptic syndromes that are refractory to medical management are those associated with complex partial seizures.
难治性癫痫的反复发作和长期用药又导致并发认知功能障碍。
The relapse paroxysm and long range difficult to cure nature falling sickness use medicine to lead to the dysfunction being complicated by cognition.
方法应用PET确定致痫灶，对59例难治性癫痫病例进行伽玛刀治疗。
Methods 59 cases ofintractable epilepsy were treated with Gamma knife and the epilepsy foci was located by PET.
对难治性癫痫病人来说，一种药不能控制发作，需联合第二种抗癫痫药。
Of refractory epilepsy patients, a drug can not control the seizures, antiepileptic drugs to be joint second.
目的提高药物难治性癫痫癫痫灶的精确定位和手术方法恰当选择的水平。
Objective To promote the level of accurate localization and appropriate treatment of surgeon of refractory epilepsy.
论述难治性癫痫的治疗方法，阐述针刺治疗的机理，提出进一步研究的思路。
The therapeutic methods of complicated epilepsia were discussed, and the mechanism of acupuncture therapy was expounded.
论述难治性癫痫的治疗方法，阐述针刺治疗的机理，提出进一步研究的思路。
Ordinary therapeutic methods are pharmacotherapy, endoscopic therapy, interpose treatment, surgical treatment and combined treatment.
这很可能与SVHRP能减轻SE后难治性癫痫大鼠对癫痫刺激的敏感性有关。
After this very possible is SVHRP can reduce se the Intractable epilepsy big rat to concern to epilepsy stimulation sensitivity.
难治性癫痫预后差，具有较高的致残率和病死率，是困扰神经科医生的一个难题。
Refractory epilepsy is with increased morbidity and mortality and poor prognosis, it has been always a difficult problem to neurological doctors.
结论难治性癫痫，尤其是内侧颞叶癫痫与人类疱疹病毒- 6感染具有明确的相关性。
ConclusionIntractable epilepsy, especially mesial temporal lobe epilepsy has a close relation ship to human herpesvirus-6.
目的研究维生素E辅助治疗难治性癫痫的临床疗效，初步探讨癫痫发病与自由基的关系。
Objective To assess the clinical effectiveness of vitamin E adjunctive therapy on intractable epilepsy in children and to approach the relation of epileptic attack and free radical.
结果药物难治性癫痫患者组脑内MRP1的表达显著高于正常对照组（P<0.01）。
Results Compared with the control group, MRP1 expression in brain specimens of medically intractable epilepsy patients showed an obviously statistical increasing(P<0.01).
本文就难治性癫痫的SPECT、PET的定位价值、表现以及神经受体显像进行了综述。
This article will review the recent research progress in SPECT, PET of intractable epilepsy, including localization value, manifestation and neuroreceptor imaging.
因此研究难治性癫痫对抗癫痫药物产生耐药的原因，并谋求新的治疗措施，具有长远的意义。
Therefore to investigate the drug resistance mechanism of refractory epilepsy, and develop new strategies for treatment may have the deep influence in future.
迷走神经刺激(VS)治疗难治性癫痫，特别是复杂部分性癫痫，能减少发作频率和发作强度。
Vagal stimulation (VS) used for intractable epilepsy, particularly those with complex partial seizures, can reduce seizure frequency and duration, or intensity.
癫痫特别是难治性癫痫的发病机制尚不完全清楚，而难治性癫痫中颞叶癫痫占据相当大的比例。
Refractory epilepsy in particular, the pathogenesis of epilepsy is not fully understood, and intractable epilepsy of temporal lobe epilepsy occupy a large proportion.
迷走神经刺激术、脑电刺激术、冷却法、放射疗法等物理疗法为难治性癫痫的治疗拓宽新的思路。
The physiotherapy including vagus nerve stimulation, brain stimulation, cooling, radiation therapy extended our thought for treating intractable epilepsy.
目的比较分析MRI检查与手术结果之间的相关性，探讨MRI对难治性癫痫的诊断和鉴别诊断价值。
Objective to compare MRI sings with surgical results, to evaluate MRI in the diagnosis and differentiation of refractory epilepsy.
手术治疗癫痫病适应于难治性癫痫病，在手术治疗癫痫之前要确定癫痫灶这样才能更好的治疗癫痫病。
Suitable for surgical treatment of epilepsy patients with refractory epilepsy, the treatment of epilepsy before surgery in order to better determine the treatment of epileptic focus epilepsy.
目的建立大鼠难治性癫痫模型并观察其特点及研究多药物耐药蛋白P-糖蛋白表达规律，探讨癫痫耐药机制。
ObjectiveTo establish and research the rat model of refractory epilepsy and investigate the rule of P-glycoprotein expression to make the mechanism of drug resistance clear.
为探讨氨己烯酸对小儿难治性癫痫的治疗价值，采用增药试验的方法，观察了该药对25例患儿的疗效及安全性。
To assess the therapeutic effectiveness of vigabatrin in the treatment of refractory epilepsy in children, the authors observed its efficacy and safety in an open add on study on 25 cases.
随着研究的深入，人们越来越多的认识到耐药基因在难治性癫痫中的作用，而多药耐药基因在难治性癫痫中扮演着重要的角色。
Following the development of research, people realize the effect of the drug resistant gene, and the multi-drug resistant gene is playing an important part in the intractable epilepsy.
随着对难治性癫痫研究的不断深入，难治性癫痫发病机制理论方面的研究已经取得许多突破性进展，促进了临床进一步研究和诊断的准确性。
With further study of refractory of epilepsy, theory study about refractory epilepsy have had breakthrough in its pathogenesy and bring more accuracy in its diagnosis and study in clinic.
术前对难治性部分性癫痫患者脑内癫痫发作的责任病灶（致癫区）的鉴定至关重要。
The identification of brain regions generating seizures ('epileptogenic zone', EZ) in patients with refractory partial epilepsy is crucial prior to surgery.
术前对难治性部分性癫痫患者脑内癫痫发作的责任病灶（致癫区）的鉴定至关重要。
The identification of brain regions generating seizures ('epileptogenic zone', EZ) in patients with refractory partial epilepsy is crucial prior to surgery.
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