基质金属蛋白酶是一类结构相关的内肽酶家族，能够降解细胞外基质成分。
The matrix metalloproteinases are a family of structurally related endopeptidases, they have the ability to degrade all components of extracellular matrix.
这些肿瘤细胞产生了一整系列的蛋白酶，能降解包围它们的细胞外基质蛋白，这也是部分的基底膜。
The tumor cells produce a whole range of proteases that degrade the proteins of the extracellular matrix that hems them in, part of which is the basement membrane.
细胞外基质(ecm)的沉积增加和降解减少是肝纤维化的主要特点。
Increased deposition of extracellular matrix (ECM) and reduced matrix degradation are the major character of liver fibrosis.
在胃癌的侵袭核转移进程中，基底膜和细胞外基质的降解是一个最重要的特征。
Degradation of basement membrane and extracellular matrix structures are important features of the metastatic process of invasion and metastasis of gastric cancer.
结论在骨关节炎中MMP1、2、3和TIMP 1、2表达异常，引起细胞外基质异常降解，是导致关节软骨发生组织学退变的原因之一。
Conclusions The abnormal expressions of MMP? 1, 2, 3 and TIMP? 1, 2, which resulted in degradation disorder of extracellular matrix, could induce degeneration of cartilage.
胃癌的侵袭和转移依赖于肿瘤间质中的血管生成和细胞外基质的降解。
The invasion and metastasis of gastric cancer depend on the angiogenesis of tumorous stroma and the degradation of extracellular matrix.
基质金属蛋白酶是一族依赖锌离子而降解各种细胞外基质的蛋白酶。
Matrix metalloproteinases (MMPs) are a large family of proteolytic enzymes, which play important roles in degradation of extracellular matrix dependent upon zinc ion.
结论：OX - LDL能促进内皮细胞表达MMP - 2，这提示血管细胞外基质的降解在氧化脂蛋白诱发的动脉粥样硬化斑块产生和破裂机制中起着一定作用。
CONCLUSION: OX-LDL enhances the expression and activity of MMP-2 in HUVEC, which may provide a explanation for the phenomenon that OX-LDL induces atherosclerotic lesions and plaque rapture.
结论：OX - LDL能促进内皮细胞表达MMP - 2，这提示血管细胞外基质的降解在氧化脂蛋白诱发的动脉粥样硬化斑块产生和破裂机制中起着一定作用。
CONCLUSION: OX-LDL enhances the expression and activity of MMP-2 in HUVEC, which may provide a explanation for the phenomenon that OX-LDL induces atherosclerotic lesions and plaque rapture.
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