目的:采用HPLC法建立快速测定大鼠血浆中阿苯达唑(ABZ)和阿苯达唑亚砜(ABZSX)的含量,为新制剂的处方筛选和药动学研究奠定基础。
Objective:To develop a rapid HPLC method for the simultaneous quantification of albendazole(ABZ) and its metabolite, albendazole sulphoxide(ABZSX), in rat plasma.
目的:采用HPLC法建立快速测定大鼠血浆中阿苯达唑(ABZ)和阿苯达唑亚砜(ABZSX)的含量,为新制剂的处方筛选和药动学研究奠定基础。
Objective:To develop a rapid HPLC method for the simultaneous quantification of albendazole(ABZ) and its metabolite, albendazole sulphoxide(ABZSX), in rat plasma.
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