比如那些富含类阿片与血清素的神经区域,在长期爱情中能够减轻焦虑与痛苦,产生一种镇定的感觉,在短期爱情中并没有出现。
For example, neural regions rich in opioids and serotonin, which relieve anxiety and pain and contribute to a sense of calm, did not light up for the newly-in-love.
同时,精神科医生应该知道“高危人群应程序化选择用药,以减轻疼痛和将阿片类药物的使用最小化。”
Meanwhile, psychiatrists should be aware that “procedural options exist to relieve pain and minimize the use of opioids in this at-risk population, ” Panchal said.
“在胚胎发育过程中,阿片类镇痛药物及其受体会起到生长调节素的作用,这或许可以解释我们的研究发现”,该研究报告著者CherylS. Broussard说道。
“Opioids and their receptors act as growth regulators during embryologic development, which may explain our findings, ” said Cheryl S. Broussard, the paper’s lead author.
因此识别那些有阿片参与控制成瘾环路的其他基因并设法绕过它们可能是治疗慢性疼痛的的更有效的另一种途径。
So identifying other genes — those that regulate the addiction circuits — and finding ways to bypass them could be another avenue to treating chronic pain more effectively with existing opiates.
痛力克是一种非甾体类抗炎药,曾被口服,肌注和静脉给药试图预防和减轻疼痛,减少对阿片类药物的需求。
Ketorolac, a nonsteroidal anti-inflammatory agent, has been administered orally, intramuscularly, and intravenously in an attempt to prevent and relieve pain and reduce opioid requirements.
研究表明,阿片类物质可能作为一种非常重要的化学物质,帮助人类大脑区别陌生人以及关系亲密的人,诸如朋友、家人和恋人。
The findings suggest that opioids might be the critical chemicals that enables human brains to distinguish between strangers and people who are closer to us, such as friends, families and lovers.
为了测试YQRFSR是否是通过对身体本身的阿片起作用,研究者对其它的动物注射一种能接合本身阿片受体导致痉挛的化合物。
To test whether YQRFSR worked via the body's natural opiate pathway, the team injected other animals with a compound known to cause spasms by tickling natural opiate receptors.
受体亲和力决定了占据一定百分比的受体所需阿片类药物的量,而内在活性决定了阿片类药物的镇痛效果。
While receptor affinity determines the amount of opioid needed to occupy a given percentage of receptors, it is the intrinsic activity of the opioid that determines its analgesic efficacy.
这些患者的疼痛程度类似,但女患者获得止痛药的几率低得多,特别是获得阿片类药物的几率比男性低15%至23%。
The men and women had similar pain scores, but women were significantly less likely to get any kind of pain medication and were 15% to 23% less likely than men to get opioids specifically.
因此,对于阿片和/或其他镇静药物的治疗中,给药治疗时间较长(如数天)的患者,为了减少戒断谵妄的危险,应花数天时间逐渐减量停药。
Opioids and/or sedatives administered for prolonged periods (i. e. , days) should be weaned over several days in order to reduce the risk of drug withdrawal.
结论:褪黑色素可通过作用于外侧缰核的阿片受体而影响其痛相关神经元对痛刺激的反应,这可能是褪黑色素中枢镇痛机制之一。
Conclusion: Melatonin can change the responses of pain neurons to pain stimulation via opioid receptor in the LHb, which might be one of analgesic mechanisms by MEL.
与热心肠的人交往感觉非常棒,事实上,科学家已经发现这是由于我们头脑中的阿片类物质被激发出来的缘故------那么,如果这同样运用于积极有用的态度时会怎样?
There's something intoxicating about warm human contact; in fact, scientists have discovered that it can generate the release of opiates in the brain—how about that for a Really Useful Attitude?
内源及外源性阿片具有调节神经元与胶质细胞的功能,这些调节具有保护或损伤脑功能的双重作用。
Endogenous and exogenous opioids can influence and modulate neuronal and glial cell function via an opioid receptor mediated mechanism, leading to either protection or damage of the brain.
贝洛克博士和他的同事们报告说,无论不停吃东西还是大量食用高脂肪食物,高糖饮食都会在控制食物摄入的大脑区域改变阿片类受体量。
Dr. Bello and colleagues report that either continuous eating or binge eating a high fat, high sugar diet alters opioid receptor levels in an area of the brain that controls food intake.
结果:中医中药用于治疗阿片类物质依赖已有百余年的历史,积累了丰富和宝贵的经验,形成了一定的特色和优势。
RESULTS it is a century history for Chinese herbs to treat substance-dependence of opium so it has plentiful and precious experience and forms a certain of advantages.
本文主要对内阿片肽在下丘脑中的分布特点及生理功能作了介绍。
In this review, the distribution and physiologic functions of endogenous opioid peptides in hypothalamus were discussed.
结论氯诺昔康用于痔疮切除手术术后镇痛是安全、有效的,能减少阿片类镇痛药的用量,副作用更少。
Intravenous Lornoxicam can effectively provide postoperative pain relief for after hemorrhoids operations with high effect and safeness, and reduce the dosage of Opium.
为探讨阿片肽与P物质(SP)的中枢升压作用的关系,我们用乌拉坦麻醉、肌肉麻痹、人工呼吸的家兔进行了实验。
To explore the relationship between opioid peptides and the sp induced pressor response, experiments were done in rabbits anaesthetized with urethane and immobilized under artificial respiration.
提示亮氨酸—脑啡肽可参与脑缺血的病理过程,血液稀释疗法也可能通过调节内源性阿片肽起作用。
The results suggest that leucine-enkephalin is probably involved in the pathophysiology of cerebral ischemia, and that hemodilution therapy may take effect by regulating endogenous opioid peptides.
结果显著影响PONV发生率的因素有性别、麻醉方式、手术时间、术后阿片类药物镇痛及既往PONV或晕动病史。
Results the obvious factors associated with PONV included gender, type of anesthesia, duration of surgery, to use opioids postoperatively and history of motion sickness.
阿片长期处理能够造成动物对阿片产生顽固性的病理性记忆,表明学习记忆参与了阿片依赖过程。
Refractory pathological memory on opioid will be generated in animals after chronic opioid treatment, which revealed the participation of learning and memory in opioid dependence.
异丁司特作为一种神经胶质激活和环核苷酸磷酸二酯酶抑制剂,已被显示有治疗神经性疼痛和阿片脱瘾的可能性。
Ibudilast, an inhibitor of glial activation and cyclic nucleotide phosphodiesterases, has shown potential in the treatment of neuropathic pain and opioid withdrawal.
阿片类药物造成的心理依赖作用提示与学习记忆功能有关。
Psychological dependence induced by opioids implicates the involvement of learning and memory function.
为了解阿片依赖者戒毒前后的个性特征,对300例阿片依赖者戒毒前与戒毒10 ~12天后采用EPQ问卷分析。
To understand the personality analyses before and after abstaining, EPQ questionnaire were conducted in 300 patients with opium dependence before and during 10-12 days after abstaining.
脑啡肽是机体产生的一种类型的缓解疼痛感觉的阿片受体,但在慢性疼痛的情况下,这些物质似乎流量不够。
Enkephalins are a type of opiate that the body produces to dull pain sensations, but in cases of chronic pain, these agents appear not to flow in sufficient quantities.
目的探讨机体微循环在阿片类耐受、戒断过程中的不同变化,探讨温阳益气活血复方抗戒断症状的作用机理;
Objective The microcirculation changes in the process of opiate dependence abstinence and the mechanisms of anti - opiate dependence - abstinence syndromes of tradibional Chinese dugs were discussed.
背景:隔-海马区的胆碱能神经通路是空间学习记忆的重要部位,此区神经元中又富含阿片受体。
BACKGROUND: the pathway of cholinergic nerve also with rich opium receptor in the septum-hippocampus areas is an important part for spatial learning memory.
本论文的工作显示了阿片类药物确实在海马的神经功能调控中起了重要作用。
The above work demonstrates that opiates play an important role in modulating the function of hippocampus.
贝洛克说,这些结果很有趣,因为我们看到随着脑部阿片受体基因的改变,它控制着我们一顿饭吃多少。
"These results are interesting because we saw changes in opioid receptor gene expression in a brain area that controls how much we eat during a meal", said Bello.
贝洛克说,这些结果很有趣,因为我们看到随着脑部阿片受体基因的改变,它控制着我们一顿饭吃多少。
"These results are interesting because we saw changes in opioid receptor gene expression in a brain area that controls how much we eat during a meal", said Bello.
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