通过动物实验,初步探讨IL-18在急性免疫性肝损伤中的意义,及早期使用IL-18抗体及时阻断细胞因子级联反应对保护肝组织的重要性。
To study rudimentarily the role of IL-18 in acute immunity hepatic injury, and the important of blocking cascade reaction of cytokines by exerting IL-18 antibody in early stage.
同时,利用此重组蛋白为抗原,制备了小鼠组织因子的小鼠源功能阻断性单克隆抗体,在血浆凝集实验中证明其对小鼠组织因子的活性有明显抑制作用。
Using this recombinant mTF as immunogen, a murine monoclonal function-blocking antibody to mTF was also generated, which can inhibit mTF-initiated plasma clotting in vitro.
采用单克隆抗体和阳性血清经elisa、阻断elisa、免疫印迹分析重组蛋白的免疫反应性。
Its immunoreactivity was analyzed by Western blot, ELISA and blocking ELISA using MAb and positive serum.
采用单克隆抗体和阳性血清经elisa、阻断elisa、免疫印迹分析重组蛋白的免疫反应性。
Its immunoreactivity was analyzed by Western blot, ELISA and blocking ELISA using MAb and positive serum.
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