方法:采用全细胞膜片钳技术,记录钠通道电流。
Methods: Whole-cell patch clamp technique was used to determine sodium channel cur rent.
目的:研究血竭对大鼠背根神经节细胞电压门控性钠通道电流的影响。
Objective: to investigate the effects of blood resin on voltage gated sodium channel current in freshly isolated rat DRG neurons.
方法用急性酶解法获得单个大鼠心室肌细胞,标准的全细胞膜片钳技术记录钠通道电流。
The whole-cell patch-clamp recording technique was used to record the change of sodium channel current influenced by carvedilol.
方法用急性酶解法获得单个大鼠心室肌细胞,标准的全细胞膜片钳技术记录钠通道电流。
MethodsAfter rat hippocampal or cerebral cortical neurons were isolated by pronase e, the IA currents were recorded by whole-cell patch clamp technique.
结论电流特性和阿米·诺利敏感性特征表明,生精细胞上所记录到的电流是上皮钠通道电流。
Conclusion the characteristics of such currents and sensitive to Amiloride all approved that these currents recorded from mouse spermatogenic cells were produced through epithelial sodium channels.
结果:血竭剂量依赖地抑制单个DRG细胞电压门控性钠通道电流,高剂量的血竭抑制作用不可逆。
The inhibition effect was irreversible at high dosage. Conclusion: blood resin inhibits the voltage gated sodium channel currents, which may well provide some analgesic effects.
方法:采用全细胞膜片钳记录法,在新鲜分离的大鼠背根神经节细胞上观察血竭对钠通道电流幅值的影响。
Method: the whole cell patch clamp recording technique was used in this study. Results: blood resin suppressed amplitude of the sodium channel currents in a dose dependent way.
目的研究在奥拉西坦作用下大鼠下丘脑神经元钠钾通道电流的变化。
Objective To study the effect of oxiracetam on the current of sodium and potassium channels in rat hypothalamic neurons.
并且离子通道活动具有明显的电压依赖性,在没有记录到钠电流的细胞记录到延迟整流钾电流。
Ion channel activity had the character of voltage-dependence. Some cells, which did not exhibit sodium currents exhibited, delayed rectifier potassium currents.
并且离子通道活动具有明显的电压依赖性,在没有记录到钠电流的细胞记录到延迟整流钾电流。
Ion channel activity had the character of voltage-dependence. Some cells, which did not exhibit sodium currents exhibited, delayed rectifier potassium currents.
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