作为直接凝血酶抑制剂，重组水蛭素在临床上的应用已越来越重要。
As a direct thrombin inhibitor, recombinant hirudin (r-hirudin) has played an important role in clinical use.
结果所制备的重组水蛭素肠溶包衣微丸药物含量质量分数为3.513%。
Results The drug content of prepared recombinant hirudin coated-pellets was 3.513% (w).
结论重组水蛭素经蟾蜍肺泡膜的转运是一个非能量依赖、非载体依赖的被动扩散过程。
CONCLUSION The transport of recombinant hirudin across xenopus pulmonary membrane was a passive diffusion process which was energy-independent and carrier-independent.
重组水蛭素鼻腔喷雾剂长期给药对鼻黏膜结构有一定影响，但此作用可在停止给药后恢复。
HVS was able to damaged the nasal epithelium, but this effect recovered soon after sloping administration.
本发明提供了一种治疗肝素相关性血小板减少症的药物组合，其主要成分包括可接受药物量的重组水蛭素及其医药上可接受的盐。
The invention provides a medicine composition for curing heparin-induced thrombocytopenia. The main components include Lepirudin and salt which can be accepted by the medicine.
本发明提供了一种治疗肝素相关性血小板减少症的药物组合，其主要成分包括可接受药物量的重组水蛭素及其医药上可接受的盐。
The invention provides a medicine composition for curing heparin-induced thrombocytopenia. The main components include Lepirudin and salt which can be accepted by the medicine.
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