目的评价乌司他丁对重症脓毒症患者的疗效和安全性，并通过观察患者细胞因子的变化来探讨其作用机制。
ObjectiveTo evaluate the efficacy and safety of ulinastatin in patients with severe sepsis and investigate its mechanisms of action.
在临床上，因脓毒血症所导致的脓毒症性休克是重症监护患者最常见的死亡原因。
Clinically, septic shock caused by sepsis is a frequent cause of death for patients in intensive care.
腹部外科中的腹腔感染、脓毒症、急性重症胰腺炎等常发生ALI/ARDS，是导致MODS、MOF以致死亡的重要原因。
The abdominal infection, sepsis and acute severe pancreatitis and so on of abdominal surgery is the important reason of dead and it often generate ALI/ ARDS and lead to MODS, MOF.
脓毒症依然是急诊和重症医学医生最常处理的危重病。
Sepsis remains one of the most common critical illnesses managed by emergency physicians and intensivists.
严重脓毒症/脓毒性休克是重症患者死亡的重要原因。
Severe sepsis and septic shock are important causes of mortality of critically ill patients.
严重脓毒症/脓毒性休克是重症患者死亡的重要原因。
Severe sepsis and septic shock are important causes of mortality of critically ill patients.
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