我们不应再花另外一个20年来重复基因疗法的总体失败。
We should not take another 20 years to repeat the general failure of gene therapy.
并根据重复基因表达(祖征)情况,认为它应属于较原始的种类。
On the basis of the charecteristics of the duplicate gene expressions (pleisiomorphy), it is regarded as a primitive species in Catostomidae.
自拟南芥以来,水稻LBD基因家族的进化经历了亚家族平行进化和重复基因的缺失这个过程。
OsLBD gene families are characterized by subclasses parallel evolution and deletion of duplicated genes from Arabidopsis.
端粒是高度重复的,从基因上来说没有意义的DNA序列,我们称之为垃圾 DNA。
Now a telomere is a highly repetitious and genetically meaningless sequence of DNA, what we were calling junk DNA.
这些平行进化同源基因是通过重复复制祖先基因而产生的。
These paralogous genes have arisen by repeated duplication of an ancestral gene.
被称为基因的启动子区域的共同特性是在转录开始时包含了一个由C字母和G字母交替重复的长序列。
It is a common characteristic of the so-called promoter regions of genes, where transcription begins, that they contain long, repetitive sequences of alternating Cs and Gs.
所不同的是细胞核可维持的DNA数量不是作为一个老的基因重复的副本,而是作为新的进化的原始材料。
The difference is the amount of DNA that could be supported in the nucleus, not as repetitive copies of the same old genes, but as the raw material for new evolution.
重复的基因在种群中散布越广,它们招致变异就越快。
The more widely the duplicated genes spread in a population, the faster they will acquire mutations.
另外有些基因,特别是由许多相同的碱基对短片段不断重复而所组成的基因,是很难很好地测序的。
And some parts, particularly those where the same short pattern of base pairs is repeated over and over again, remain difficult to sequence well.
如果把人类基因组视作“生命之书”,他们绘制了大量字母或短语的变异——但忽视了“书”中篇幅更大的整页乃至整章的删节和重复内容。
Looking at the human genome as a "book of life" they have mapped vast Numbers of variations in letters or short words - but missed much larger deletions and duplications of pages or chapters.
虽然从技术角度来看,人类基因组项目非常庞大,其实它只不过是由数百万经巧妙编排的小型重复行为的总和。
Though a technical tour-de-force, the Human Genome Project was actually the sum of millions of small, repetitive actions by cleverly programmed robots.
大多数情况下,基因的重复和缺失并不会对人体造成任何影响,但某些情况下它们会导致疾病。
In many cases, duplications and deletions have no effect, but occasionally they can lead to disease.
“基因包”里包含有经修饰过的基因,并且能够让生物体重复利用氧化荧光素,这种次级代谢产物还可以用于二次发光。
The package includes genetic modifications to enable organisms to recycle oxyluciferin, the by-product of the reaction that produces light.
这一模式是随着基因学研制出新一代的药物而重复出现。
This is a pattern seen again and again with the new generation of drugs that genomics has helped to create.
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
它称为MECP2重复综合症,当人类,尤其是男孩,遗传两组MECP2基因时就会出现这种障碍。
That disorder, MECP2 duplication syndrome, occurs when people, especially boys, inherit two copies of the MECP2 gene.
这些改变可能包括基因组的大量缺失,或者额外重复片断的增加,特别是快速突变和常见的变异。
Such changes could include wholesale deletions of chunks of the genome or additions of extra copies. Cancer genomes, in particular, mutate rapidly and contain frequent abnormalities.
所以事实上他们所作的是检测构成以前大流行病毒株基因表达的蛋白的成分并且寻找这些病毒株间交叉的重复模式。
So in effect what they did was scan all the building blocks of proteins that all the genes of previous pandemic strains expressed and looked for repeated patterns across the strains.
这些缺失或者是重复,也被称做是拷贝数的改变,能改变一个基因的数目。
These deletions or duplications, also called copy-number changes, can change the dosage of a gene.
目的探讨汉族人群中脑源性神经营养因子(BDNF)基因(GT)n二核苷酸重复多态与精神分裂症阴性亚型发病之间的关系。
Objective To explore the relationship between (GT)n dinucleotide repeated polymorphism of the brain-derived neurotrophic factor (BDNF) gene and onset of negative subtype schizophrenia in Chinese.
如果调控紊乱,则基因组畸变累积,如重复的DNA序列甚至出现整条多余的染色体。
When regulation fails, genome aberrations accumulate, including repeated sequences of DNA or een entire extra chromosomes.
CA重复序列基因测序未见异常。
部分串联复制是基因突变的一个类型,当一个基因片断重复时发生,就像停顿基因。
A partial tandem duplication is a type of gene mutation that occurs when a section of a gene is repeated, like a stutter in the gene's DNA.
发现与母本水稻相比,远缘杂交后代高粱稻基因组在中度重复顺序部分发生了变化。
It was found that by comparison with its mother plant rice, an apparent change had happened in the middle repeated sequence component of the stable hybrid.
我们自己制备的LZF—I探针,能与鱼类基因组DNA中的简单重复序列杂交形成杂交分子。
The oligonucleotide probe LZF-I, which is synthesized by us, can form thehybrid molecules with the simple repetitive DNA of three species of fishes.
各种作物基因组大小的差异可能由于各个区段内基因间重复顺序扩增的程度不同所致。
The differences of genome size among cereals may be due to different degrees of repetitive sequence amplification in intergenic regions in different species.
因每个SSR序列的基本单元重复次数在不同基因型间差异很大,从而形成其座位的多态性。
The repeat times of basic units of each SSR sequence are different among different genotypes, so polymorphism of the seat is formed.
因每个SSR序列的基本单元重复次数在不同基因型间差异很大,从而形成其座位的多态性。
The repeat times of basic units of each SSR sequence are different among different genotypes, so polymorphism of the seat is formed.
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