• 体外速率符合一级动力学模型

    The in vitro release characteristics investigated fitted to first order pharmacokinetic model.

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  • 其为载体制备纳曲微球比较了体外释药速率

    Invitro release of naltrexone microspheres prepared with the various PLGA were compared.

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  • 目的研究藤黄骨架体外速率影响因素

    Objective To study the influential factors of the release rate of neogambogic acid from sustained release matrix tablets.

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  • 在所考察硬度范围内,释药速率随硬度增加而减慢

    The release rate decreased with the increase of hardness in the range investigated.

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  • 结论:速率离子强度之间存在较好的线性负相关关系。

    CONCLUSIONS the rate of drug release is proportional to the ionic strength.

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  • 比较层中不同及其用量微丸药速率影响

    The influences of different pore-forming agents and their amount on the drug release were compared.

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  • 结果透膜速率小于溶出速率白菜素渗透片的药速率

    RESULTS The influx of water that passed the osmotic pump tablet was greatly less than the drug dissolution rate from tablet core and the bergenin release rate.

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  • 结果:发现凝胶剂中加入适量PVP增加凝胶粘结力,又可一定范围内控制释药速率

    Results: With the addition and amount of PVP into the gels, the stickiness of gels was increased and the drug releasing rates were controlled over a suitable rate range.

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  • 因素考察发现,影响时滞释药速率主要因素溶胀中高效崩解剂比例、溶胀层增重层增重。

    The factors which affect the lag time and drug release behavior were investigated, such as the thickness of the inner and outer layers, the amount of PVPP and other excipients, etc.

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  • 通过透射电镜观察、动态光散射测定紫外吸光度测定等手段分析微观形态粒径大小、测定了载胶束的体外释药速率

    Microscopic morphology, diameter and drug-loaded amount of the micelles were examined by means of TEM, DLS and UV respectively, and their in vitro drug release rates were measured.

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  • 方法采用相似因子考察影响速率因素,并考察了其释药机理。

    Methods the influencing factors on the drug release were investigated by use of similarity factor method.

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  • 的初始速率传统经皮系统相近释药量与储库层物含量无关;

    The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.

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  • 盐酸维拉帕米模型,制备了口服渗透片。通过考察渗透泵片体外过程速率研究口服渗透泵制剂释药基本过程及其特性

    The main processes of the drug delivery of oral osmotic pump system were studied to investigate its delivery characteristics, with verapamil hydrochloride as the model drug.

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  • 盐酸维拉帕米模型,制备了口服渗透片。通过考察渗透泵片体外过程速率研究口服渗透泵制剂释药基本过程及其特性

    The main processes of the drug delivery of oral osmotic pump system were studied to investigate its delivery characteristics, with verapamil hydrochloride as the model drug.

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