体外释药速率符合一级动力学模型。
The in vitro release characteristics investigated fitted to first order pharmacokinetic model.
以其为载体制备纳曲酮微球,比较了体外释药速率。
Invitro release of naltrexone microspheres prepared with the various PLGA were compared.
目的研究新藤黄酸骨架片体外释药速率的影响因素。
Objective To study the influential factors of the release rate of neogambogic acid from sustained release matrix tablets.
在所考察的硬度范围内,释药速率随硬度的增加而减慢;
The release rate decreased with the increase of hardness in the range investigated.
结论:释药速率与离子强度之间存在较好的线性负相关关系。
CONCLUSIONS the rate of drug release is proportional to the ionic strength.
比较了缓释层中不同致孔剂及其用量对微丸释药速率的影响。
The influences of different pore-forming agents and their amount on the drug release were compared.
结果水透膜的速率远小于片芯中药物的溶出速率及岩白菜素渗透泵片的释药速率;
RESULTS The influx of water that passed the osmotic pump tablet was greatly less than the drug dissolution rate from tablet core and the bergenin release rate.
结果:发现凝胶剂中加入适量PVP既可增加凝胶的粘结力,又可在一定范围内控制释药速率。
Results: With the addition and amount of PVP into the gels, the stickiness of gels was increased and the drug releasing rates were controlled over a suitable rate range.
单因素考察发现,影响释药时滞和释药速率的主要因素为溶胀层中高效崩解剂比例、溶胀层增重及控释层增重。
The factors which affect the lag time and drug release behavior were investigated, such as the thickness of the inner and outer layers, the amount of PVPP and other excipients, etc.
通过透射电镜观察、动态光散射测定、紫外吸光度测定等手段分析胶束的微观形态、粒径大小和载药量、测定了载药胶束的体外释药速率。
Microscopic morphology, diameter and drug-loaded amount of the micelles were examined by means of TEM, DLS and UV respectively, and their in vitro drug release rates were measured.
方法采用相似因子法考察影响药物释放速率的因素,并考察了其释药机理。
Methods the influencing factors on the drug release were investigated by use of similarity factor method.
药物的初始释放速率和传统经皮给药控释系统相近,释药量与储库层药物含量无关;
The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.
以盐酸维拉帕米为模型药物,制备了口服渗透泵片。通过考察渗透泵片体外释药各过程的速率,研究口服渗透泵制剂释药的基本过程及其特性。
The main processes of the drug delivery of oral osmotic pump system were studied to investigate its delivery characteristics, with verapamil hydrochloride as the model drug.
以盐酸维拉帕米为模型药物,制备了口服渗透泵片。通过考察渗透泵片体外释药各过程的速率,研究口服渗透泵制剂释药的基本过程及其特性。
The main processes of the drug delivery of oral osmotic pump system were studied to investigate its delivery characteristics, with verapamil hydrochloride as the model drug.
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