目的:制备微泡型口腔速释片。
AIM: To develop the micro-effervescing fast-release oral tablet.
以释放试验研究了缓释片的释药机理。
The release mechanism was investigated through the dissolution tests.
目的制备别嘌醇缓释片并探讨其释药机理。
Objective To prepare the allopurinol sustained-release tablets and study the release mechanism.
目的:制备具零级释药特征的丹皮酚缓释片。
Objective: To prepare Paeonol Sustained-release Tablets of zero order release.
目的:研制马尼地平缓释片,并考察其释药机制。
Objective: To prepare manidipine sustained-release tablets and to investigate the release mechanism.
结果:制备的黄杨宁渗透泵控释片体外释药速度较平稳。
Results:Preparation of Huangyangning osmotic pump controlled release tablets in vitro release rate of more stable.
结论黄杨宁缓释片有较好的缓释作用,释药以扩散为主。
Conclusion HSRT have a better release effect in the test condition and its release is in a way of diffusion mainly.
结果:该处方、制备工艺简单,体外释药符合缓释片的规律。
RESULTS Prescription and process are simple and the in vitro drug released complied with relevant requirement.
目的建立罗通定缓释片体外释放度测定方法,评价其体外释药行为。
Objective to establish a UV method to determine the release degree of rotundine sustained-release tablets and to evaluate its in-vitro release behavior.
结论阿魏酸钠单层渗透泵控释片工艺稳定,呈明显的零级释药特征。
Conclusion The drug release of sodium ferulate single-layer osmotic pump controlled release tablets is stable and had obvious characteristic of zero release.
目的以羟丙甲基纤维素为骨架材料制得灯盏花素缓释片,并对释药机制进行探讨。
OBJECTIVE Breviscapine sustained-release tablets(BST)were formulated with hydroxypropyl-methylcellulose as the matrix material and the release mechanism of the tablets was studied.
结论:盐酸氨溴索渗透泵控释片释药稳定,零级释药明显,具备优良控释制剂的特征。
Conclusions: The ambroxol HCl osmotic pump controlled release tablets have a stable release curve and conform to zero release order.
目的:建立复方丹参缓释片多指标成分的体外释放度测定方法,评价其体外释药行为。
Objective: to develop the methods to determine the in vitro release of multi-target ingredients in Compound Danshen Sustained-release Tablets and to evaluate its release behavior in vitro.
亲水凝胶骨架缓释片的释药过程与相转变过程、凝胶层屏障及区域前沿移动行为密切相关。
The phase transition, barrier function and front movement of the gel layer are closely related to drug release process of hydrophlic gel matrix sustained-release tablets.
结论联合应用不同黏度和用量的HPMC,可制备具有理想释药行为的布洛芬骨架缓释片。
Conclusions Ibuprofen sustained release tablets with ideal release behavior could be prepared by selecting HPMC with different viscosity and adjusting the content of HPMC.
结果表明,制得的酒石酸美托洛尔缓释片具有明显的缓释作用,体外释放符合一级释药动力学规律。
The results indicated that the sustained-release tablets had an expected sustained-release quality, and drug release pattern was in accorded with the first order kinetics.
结论:两种制剂具生物等效性,且缓释片比常释片有峰谷浓度差异小、血药浓度波动幅度小的特点。
CONCLUSION: The two formulations were bioequivalent and the sustained release tablet showed smaller difference between C max and C min and smaller DF compared with the ordinary tablet.
膜片弹簧中间的部分撕裂成若干个指针大小般的片,充当回力(释力)杠杆。
The center portion of the diaphragm spring is slit into numerous fingers that act as release levers .
目的制备度米芬渗透泵片,以控制体外释药维持零级释放达80%以上。
Objective To prepare Domiphen osmotic tablets of zero release above 80% in vitro.
结论:通过选择片芯中的崩解剂、调整包衣层组成和厚度,可以用包衣的方法得到不同时间脉冲释药的阿司匹林片剂。
Conclusion: the pulsatile release of aspirin can be controlled by selection of disintegrants of the core and changing composition and thickness of the coating film.
结论口颊黏附片的生物黏附性与体外释药行为具有一定的相关性,通过调整处方可筛选出生物黏附性和体外释药均较理想的处方。
CONCLUSION the adhesive property of the tablets and the release behavior of drug are relevant. Also, the formulation of buccal adhesive tablets is optimized by adjusting the composition.
目的以对乙酰氨基酚(扑热息痛)为模型药物制备新型口服速释剂型口腔崩解片。
OBJECTIVE To develop a novel rapidly release oral solid dosage form orally disintegrating tablet using acetaminophen as the model drug.
目的研制三七总皂苷生物黏附片,考察其体外释药动力学、对离体肠黏膜的黏附力。
OBJECTIVE To prepare the Panax Notoginseng Saponines (PNS) bioadhesive tablets, and to study their release kinetics and bioadhesive tablets force to rabbit small intestine in vitro.
目的制备酒石酸托特罗定渗透泵片,考察其体外释药特性。
OBJECTIVE to prepare the tolterodine osmotic pump tablet and study its release profiles in vitro.
目的:优化银杏叶分散片处方,制备中药口服固体速释制剂。
Objective: To optimize the formulation of the Ginkgobiloba immediate release tablet.
介绍了TLD-3500热释光读出器和GR-100M型热释光剂量片构成的探测器在脉冲硬X射线辐射参数测量中的应用。
This paper introduces the application of thermoluminescence dosimeter(TLD) which composed by TLD3500 reader and GR100M chips on the measurement of hard Xray pulse energy spectrum.
优选由那格列奈速释层与盐酸二甲双胍缓释层组成的双层片处方。
To optimize the formula of the double-layer tablet of nateglinide rapid-release layer and metformin hydrochloride sustained-release layer.
综述了胃漂浮片的释药机理、适用性、处方组成及制备中的关键影响因素等方面的内容,并列举一些新型剂型实例;综述。
The release mechanism, applicability, formulation ingredients of floating drug delivery system were summarized. And some new forms of this system were exemplified.
目的:解决硫酸沙丁胺醇延迟释放片定时释药问题。
Objective:To Study the preparation and dissolution in vitro of salbutamol sulfate delayed -release tablets.
目的:考察芦丁缓释骨架片释药机制的影响因素。
Objective: to study the factors influencing the release mechanism of rutin from sustained release matrix tablets.
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