目的研究TRAIL基因结合端粒酶启动子特异性靶向治疗的作用。
To explore the targeted gene therapy of tumors by using the TRAIL gene in combination with the telomerase promoter.
目的：研究TRAIL基因结合端粒酶启动子特异性靶向治疗的作用。
AIM: To explore targeted gene therapy of tumor by using the combination of TRAIL gene with the telomerase promoter.
目的：研究凋亡因子TRAIL结合端粒酶启动子对肿瘤的特异性杀伤作用。
OBJECTIVE: to investigate the specificity role of the apoptosis factor TRAIL gene with telomerase promoter in tumor gene therapy.
通过双荧光素酶报告基因测定法测定了IGFBP-3对由三碘甲状腺素刺激的生长激素启动子活性的影响。
The effect of IGFBP-3 on the growth hormone promoter activity stimulated by triiodothyronine was determined by dual-luciferase reporter assay.
结论：成功构建了缺氧应答启动子的荧光素酶报告载体，为进一步研究其缺氧调控作用提供了条件。
CONCLUSION: Luciferase reporter vectors regulated by HRE/CMV promoters were successfully constructed, which makes it possible to further investigate their potency of hypoxia regulation.
随后人GRP94启动子克隆了荧光素酶基因上游区且缺氧环境中活性增强。
The human GRP94 promoter was then cloned upstream of the luciferase gene and showed enhanced activity in hypoxic conditions.
TK的结构中，含有ALBTRS启动子，具有在表达白蛋白的肝细胞中特异表达的潜能，载体经酶切鉴定表明结构符合要求。
TK contained ALBTRS promoter sequence which probably control the targeting expression in hepatocyte of target gene TK. The enzyme cut assay of the vector LN. ALBTRS.
研究植物脂肪酸延长酶基因FAE1的启动子，对了解长链脂肪酸合成的分子机制以及油菜籽油成分的基因工程改良具有重要的指导意义。
Research on FAE1 promoter is important to learn the molecular mechanism of very-long-chain fatty acid biosynthesis and genomic engineering development of rapeseed oil components.
目的建立甲基化特异性PCR（MSP）技术检测黏着斑激酶相关性鸟苷三磷酸酶调节因子（GRAF）基因启动子甲基化。
Objective To establish the methylation-specific PCR(MSP) to detect methylation of GTPase regulator associated with the focal adhesion kinase(GRAF) gene promoter.
目的：探讨混合型高脂血症与肝脂酶基因启动子250G/A多态性的关系。
Objective To study the interaction between hepatic lipase gene-250G/A polymorphism and combined hyperlipidemia.
外源淀粉水解酶能在酵母中高效表达并分泌，其主要因素在于：在构建载体时组入强启动子；
The main factors for high efficiency expression and secretion of exogenous amylum hydrolase in S. cerevisiae are as follows: involvement of strong promoter in carrier construction;
启动子的激活、高糖刺激、炎性因子、自由基、十二脂氧化酶、前列腺素E等多种因素的作用下，COX-2表达显著上调。
The interaction of promoter activity, stimulation of hyperglycemia, inflammatory factors, free radicals, 12-lipoxygenase, prostaglandin E and other factors induces the expression of COX-2.
本发明描述了新的脂氧化酶基因及从其中衍生的启动子、转运肽和蛋白质。
This invention describes novel lipoxygenase genes and promoters, transit peptides and proteins derived therefrom.
结果构建并鉴定了系列截短的NOS1 启动子萤光素酶报告基因载体；
Results A series of truncated NOS1 promoter luciferase reporter vectors were constructed and identified.
目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动子荧光素酶报告基因载体，并验证其转录活性。
ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.
目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动子荧光素酶报告基因载体，并验证其转录活性。
ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.
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