为什么不将脂酰辅酶 A直接运输到线粒体中？
Why isn't the fatty acyl coa transported into the mitochondria directly?
其合成多在微生物中进行，原料为磷酸甘油和脂肪酰辅酶a。
They are synthesized from glycerol phosphate and fatty acyl CoAs, usually in the microsomes.
脂肪酸合成酶(FAS)催化乙酰辅酶a和丙二酰辅酶A合成长链脂肪酸。
Fatty acid synthase (FAS) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA.
当加入琥珀酰辅酶A，曲线便转换成右边那条，对乙酰辅酶A浓度的依赖更加显著。
When succinyl-CoA is added, the curve shifts to the right and the sigmoid dependence is more pronounced.
该单克隆抗体是由合成的人源酰辅酶A羧化酶蛋白丝氨酸(79位)的肽段免疫动物而制备的。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser79 of human acetyl-CoA carboxylase protein.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
甲基丙二酸血症是由于甲基丙二酰辅酶A变位酶或其辅酶腺苷钴胺素缺陷所致的一种遗传性代谢疾病。
Methylmalonic acidemia is an inherited metabolic disorder, which is caused by deficiency of methylmalonyl-coenzyme a mutase or its cofactor adenosylcobalamin.
抑制脂肪代谢相关酶脂蛋白脂酶、硬脂酰辅酶A 脱氢酶、脂肪酸合成酶等的活性来产生降脂作用。
CLA may inhibit the enzymes, lipoprotein lipase(LPL), stearoyl-CoA desaturase(SCD), fatty acid synthase(FAS)and so on, which are related to lipid metabolism.
他汀类药物能阻断羟甲基戊二酸单酰辅酶A还原酶，该酶与多种脂肪的产生有关，阻断该酶可以降低胆固醇水平。
Smoke breakStatins block an enzyme called HMG-CoA reductase, which is involved in the production of various fatty molecules. Blocking this enzyme lowers cholesterol levels.
结论：普伐他汀不能抑制肝细胞PAI-1的分泌。羟甲基戊二酰辅酶A还原酶的抑制与PAI- 1分泌可能没有关系。
Conclusion:Pravastatin can not inhibit the secretion of PAI 1 in hepatic cells and the inhibition of hydroxymethylglutaryl coenzyme A reductase may not be related to the secretion of PAI 1.
桂酰辅酶A还原酶基因(CCR)控制木质素含量和组成，而且与桉属木材强度特性有密切关联，因此CCR与造纸和实木利用紧密相关。
The Cinnamoyl CoA reductase (CCR) gene is involved in determining lignin content and composition in plant secondary cell walls and has been associated with wood strength characteristics in Eucalyptus.
长链酰基辅酶A合成酶把游离脂肪酸活化成为酰基辅酶A。
Long-chain acyl-coenzyme A synthetases activate free fatty acid to acyl-CoA thioesters.
所有活细胞中的辅酶，起酰群载体作用，肪脂酸的合成和氧化、丙酮酸酯的氧化和其他工酰基反应中不可缺少。
A coenzyme present in all living cells that functions as an acyl group carrier and is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation reactions.
酰基辅酶A：胆固醇酰基转移酶（ACAT）是细胞内唯一合成胆固醇酯的酶，在细胞和生物体胆固醇代谢平衡中起非常重要的作用。
Acyl-CoA: cholesterol acyltransferase(ACAT) is an intracellular enzyme that catalyzes the formation of cholesterol esters from long-chain fatty acyl coenzyme A and cholesterol.
目的：观察酰基辅酶a：胆固醇酰基转移酶1 (ACAT1)反义寡核苷酸对泡沫细胞(FC)形成的影响。
AIM: To study the effect of acyl coenzyme a: cholesteryl acyltransferase 1 (ACAT1) antisense oligonucleotides on the formation of foam cells (FC).
研究显示恩镰孢菌素是一个离子载体，最近，它们对酰基辅酶A胆固醇转移酶的效应、杀线虫活性和选择性的抗肿瘤活性得到了更多的关注。
The enniatins have been shown to act as ionophores. Recently their effects on acyl-CoA cholesterol transferase, as nematocides and the selectivity of their antitumor action have received more focus.
目的：观察牛磺酸对THP - 1及THP - 1源性巨噬细胞酰基辅酶a：胆固醇酰基转移酶1 (ACAT - 1)表达及活性的影响。
Objective: To investigate the role of taurine in acyl-coenzyme a: cholesterol acyltransferase-1 (ACAT-1) expression and activity in THP-1 and THP-1-derived macrophages.
长链酰基辅酶A是脂肪的活性代谢形式，且他们在细胞中相当容易形成。
Among the things that we know stimulate lipolysis are the long-chain acyl-CoA.
长链酰基辅酶A合成酶（LACS）把游离脂肪酸活化成为酰基辅酶A，从而在生物的脂肪酸的合成代谢和分解代谢中起着重要的作用。
Long-chain acyl-coenzyme A synthetases(LACSs)activate free fatty acid to acyl-CoA thioesters and play an important role in fatty acid anabolism and catabolism.
长链酰基辅酶A合成酶（LACS）把游离脂肪酸活化成为酰基辅酶A，从而在生物的脂肪酸的合成代谢和分解代谢中起着重要的作用。
Long-chain acyl-coenzyme A synthetases(LACSs)activate free fatty acid to acyl-CoA thioesters and play an important role in fatty acid anabolism and catabolism.
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