在氟化钾催化下,芳香醛与氰乙酸乙酯发生克脑文格尔缩合反应,得到高产率的缩合产物。
The knoevenagel condensation of aromatic aldehydes with ethyl cyanoacetate proceeds smoothly in the presence of potassium fluoride giving products in high yield.
讨论了以草酸二乙酯为原料,经过克莱森缩合、环合、氨解反应合成5甲基异唑3甲酰胺工艺的改进。
This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.
在氟化钾催化下,芳香醛与氰乙酸乙酯发生克脑文格尔缩合反应,得到高产率的缩合产物。且只得到E式异构体。
The knoevenagel condensation of aromatic aldehydes with ethyl cyanoacetate proceeds smoothly in the presence of potassium fluoride giving products in high yield. Only the E isomers could be isolated.
以聚乙二醇- 200与丙烯酸直接缩合反应,在不加有毒带水剂的条件下合成了丙烯酸聚乙二醇单酯。
Acrylate polyethylene glycol monoester was synthesized by condensation of PEG (200) and acrylic acid without water-carrying reaction.
加恒沸剂共沸蒸馏和乙酸萃取反应精馏过程。乙醛缩合法生产乙酸乙酯的三塔连续精馏过程以及乙烯与乙酸气相催化反应的加水精制工艺过程。
Three-tower continuous distillation process of ethyl acetate from aldehyde condensation and purification by gas-phase oxidation of acetic acid and ethylene were also discussed.
方法:由葡萄糖通过缩合、氧化、去保护、酯化反应制备水杨酸葡萄糖酯。
Methods: Salicylic acid glucose esters were synthesized from glucose by condensation, oxidization, deprotection and esterification.
方法:以庚二酸单乙酯为原料,经酰氯化、傅克酰化、还原、水解、缩合及氧化反应合成塞曲司特。结果:塞曲司特的总产率为5 0 .7%。
Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.
第二种聚 酰亚胺聚合物是芳香族四酸二酐与芳香族二异氰酸酯,在有机溶剂中,在催化剂的作用下,一步法缩合反应制备得到;
The second polyimide polymer is prepared with aromatic tetracid dihydride and aromatic diisocyanate and through a one-step condensation reaction in organic solvent and under the action of catalyst.
对溴苯酚经烷基化、硫酸二甲酯醚化、缩合及水解反应制得阿达帕林,总收率51%。
Adapalene was synthesized from 4-bromophenol by alkylation, etherification, condensation and hydrolysis with an overall yield of 51%.
以对甲苯乙酮和三氟醋酸乙酯为原料,经缩合、环合两步反应得到2型环氧酶抑制剂赛来昔布,总收率为6 7%。
Celecoxib as a cyclooxygenase-2 inhibitor, was synthesized from p-methylacetophenone and ethyl trifluoroacetate by successively condensation and cyclization in 67% overall yield.
以对甲苯乙酮和三氟醋酸乙酯为原料,经缩合、环合两步反应得到2型环氧酶抑制剂赛来昔布,总收率为6 7%。
Celecoxib as a cyclooxygenase-2 inhibitor, was synthesized from p-methylacetophenone and ethyl trifluoroacetate by successively condensation and cyclization in 67% overall yield.
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