• 氟化催化下,芳香乙酸乙发生克脑文格尔缩合反应,得到高产缩合产物

    The knoevenagel condensation of aromatic aldehydes with ethyl cyanoacetate proceeds smoothly in the presence of potassium fluoride giving products in high yield.

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  • 讨论了以草酸二乙为原料,经过克莱森缩合、环合、氨解反应合成5甲基异唑3甲酰胺工艺改进

    This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.

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  • 氟化催化下,芳香乙酸乙发生克脑文格尔缩合反应,得到高产率的缩合产物。且得到E异构体

    The knoevenagel condensation of aromatic aldehydes with ethyl cyanoacetate proceeds smoothly in the presence of potassium fluoride giving products in high yield. Only the E isomers could be isolated.

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  • 以聚乙二醇- 200丙烯酸直接缩合反应在不加有毒带水剂的条件下合成了丙烯酸聚乙二醇单

    Acrylate polyethylene glycol monoester was synthesized by condensation of PEG (200) and acrylic acid without water-carrying reaction.

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  • 加恒沸剂共沸蒸馏乙酸萃取反应精馏过程乙醛法生产乙酸三塔连续精馏过程以及乙烯乙酸气相催化反应加水精制工艺过程。

    Three-tower continuous distillation process of ethyl acetate from aldehyde condensation and purification by gas-phase oxidation of acetic acid and ethylene were also discussed.

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  • 方法葡萄糖通过缩合氧化、去保护、反应制备水杨酸葡萄糖

    Methods: Salicylic acid glucose esters were synthesized from glucose by condensation, oxidization, deprotection and esterification.

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  • 方法:以庚二酸单乙原料,氯化、傅克酰化、还原、水解、缩合氧化反应合成塞曲司特。结果:塞曲司特总产率为5 0 .7%。

    Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.

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  • 第二种聚 酰亚胺聚合物芳香族四酸二酐芳香族二异氰酸有机溶剂中,在催化剂作用一步法缩合反应制备得到;

    The second polyimide polymer is prepared with aromatic tetracid dihydride and aromatic diisocyanate and through a one-step condensation reaction in organic solvent and under the action of catalyst.

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  • 对溴苯酚烷基化硫酸二甲醚化缩合水解反应制得阿达帕林,收率51%。

    Adapalene was synthesized from 4-bromophenol by alkylation, etherification, condensation and hydrolysis with an overall yield of 51%.

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  • 以对甲苯三氟醋酸乙为原料,缩合环合两步反应得到2型环氧抑制剂赛来布,收率为6 7%。

    Celecoxib as a cyclooxygenase-2 inhibitor, was synthesized from p-methylacetophenone and ethyl trifluoroacetate by successively condensation and cyclization in 67% overall yield.

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  • 以对甲苯三氟醋酸乙为原料,缩合环合两步反应得到2型环氧抑制剂赛来布,收率为6 7%。

    Celecoxib as a cyclooxygenase-2 inhibitor, was synthesized from p-methylacetophenone and ethyl trifluoroacetate by successively condensation and cyclization in 67% overall yield.

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