• 目的建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定

    Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.

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  • 目的探索肝硬化时组织细胞胰岛素受体(IR)酪氨酸蛋白激酶(TPK)含量变化规律。

    Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.

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  • 许多炎症性疾病感染性休克(9),银屑病(10),酪氨酸蛋白激酶活动表现变化

    In many inflammatory diseases such as septic shock (9), and psoriasis (10) the change in protein tyrosine kinase activity has been shown.

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  • 结论AG110 9不仅酪氨酸蛋白激酶抑制剂而且一种十分有效蛋白激酶CK2的抑制剂。

    CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.

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  • 本文丁酸诱导分化白血病细胞株k- 562细胞胰岛素受体酪氨酸蛋白激酶细胞内源性底物进行了研究。

    In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.

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  • 非替尼为选择性EGFR一蛋白酪氨酸激酶抑制剂阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡

    Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

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  • 受体酪氨酸蛋白激酶细胞信号转导进行关键信号酶,生长因子调控细胞生长、发育功能过程中起重要生理作用

    Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.

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  • JANEX- 1具有良好抗白血病活性诱导酪氨酸蛋白激酶过度表达淋巴性白血病细胞髓性白血病细胞凋亡

    JANEX-1 exhibits significant anti-leukemia activity, which could induce apoptosis in human lymphoblastic as well as myeloblastic leukemia cells with over-expressed tyrosine protein kinase.

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  • 对丁酸转化前后红白血病细胞k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性细胞内源性底物进行了研究

    In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.

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  • 应用受体放射配基结合分析法测定甜菜碱对大鼠肝细胞膜表皮生长因子受体EGF)及其酪氨酸蛋白激酶TPK)有显著结合抑制作用

    Using radioligand of binding assay of receptors determinates that betaine can inhibit the binding of EGF receptor with EGF and affect the TPK activity conspicuously.

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  • 方法通过外源性底物磷酸化方法,测定了16正常皮肤22银屑病皮损、5 例皮肤鳞组织角质形成细胞膜酪氨酸蛋白激酶( T PK活性

    Method The activity of tyrosine protein kinase(TPK) was determined by using exogenic substrates in 16 samples of normal skin, 22 psoriatic lesion and 5 skin squamous carcinoma.

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  • 方法通过外源性底物磷酸化方法,测定了16正常皮肤22银屑病皮损、5 例皮肤鳞组织角质形成细胞膜酪氨酸蛋白激酶( T PK活性

    Method The activity of tyrosine protein kinase(TPK) was determined by using exogenic substrates in 16 samples of normal skin, 22 psoriatic lesion and 5 skin squamous carcinoma.

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