经尿素变性、梯度透析复性及去除GST“标签”后，获得重折叠的人EGFR胞内酪氨酸激酶结构域蛋白。
After denaturing in urea, gradient dialysis and cleavage of GST-tag, refolded human EGFR-TKD was obtained.
提供了用于在具有次级EGFR突变，特别地酪氨酸激酶结构域突变的抗标准疗法的个体中治疗癌症和减少肿瘤生长的方法。
Methods for treatment of cancer and reduction of tumor growth in individuals with secondary EGFR mutations, particularly tyrosine kinase domain mutations, resistant to standard therapy are provided.
提供了用于在具有次级EGFR突变，特别地酪氨酸激酶结构域突变的抗标准疗法的个体中治疗癌症和减少肿瘤生长的方法。
Methods for treatment of cancer and reduction of tumor growth in individuals with secondary EGFR mutations, particularly tyrosine kinase domain mutations, resistant to standard therapy are provided.
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