环境所引发的基因变异被称为“表观遗传变化”,它可能会影响基因被激活的时间、被激活的程度以及它如何与邻近基因相互配合。
Environmentally triggered alterations in genes - known as epigenetic changes - can affect when a gene is activated, how robustly it is turned on and how it interacts with neighboring genes.
结论在中国汉族人群中GRIK2基因或邻近基因可能是精神分裂症和心境障碍的共同易患基因之一,并可能影响发病年龄。
Conclusion: the GRIK2 gene or neighboring gene may be one of common susceptible genes for schizophrenia and mood disorders in Chinese Han population, also may affect the age of onset.
结论在中国汉族人群中5-HTR6基因或邻近基因可能是精神分裂症易患基因之一,但可能不是心境障碍的易患基因。
Conclusion: The 5 - HTR 6 gene or neighboring gene may be one of common susceptible genes for schizophrenia, but not for mood disorders in Chinese Han population.
相反这些缺陷主要位于基因完全或部分开合的邻近区域里。
Instead the defects lay mainly in adjacent regions that turn the gene fully or partially on and off.
结论:根据肿瘤及其邻近组织的基因表达特征,我们建立了一个HCC复发的复合预后模型。
CONCLUSIONS: We developed a composite prognostic model for HCC recurrence, based on gene expression patterns in tumor and adjacent tissues.
HIV病毒除去“否因”与邻近的一些基因物质后,是否真如迪肯和他的同僚审慎暗示的一样,可以作为艾滋病疫苗的基础?
Could HIV itself, stripped of nef and adjacent sections of genetic material, provide the basis for such a vaccine, as Deacon and his colleagues cautiously suggest?
分子杂交结果显示,编码功能蛋白的基因及其邻近顺序存在相当程度的保守性。
Southern hybridization results showed that coding sequences and neighboring sequences of genes were relatively conserved.
并对发现突变的基因进行分析。方法应用PCR扩增、DNA序列测定等技术分析所有AR基因外显子及其邻近DNA序列片段;
Methods PCR and DNA sequencing were performed to study the AR gene mutation; Mbo I restriction endonuclease was used to detect existence of the mutation in normal controls;
并对发现突变的基因进行分析。方法应用PCR扩增、DNA序列测定等技术分析所有AR基因外显子及其邻近DNA序列片段;
Methods PCR and DNA sequencing were performed to study the AR gene mutation; Mbo I restriction endonuclease was used to detect existence of the mutation in normal controls;
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