目的介绍ICH关于遗传毒性研究的指导原则修订的最新进展。
Objective To introduce the latest progress of ICH S2 revisions.
目的研究吸烟与温石棉对细胞的遗传毒性。
Objective to study the genetic toxic effect of cigarette smoking and chrysotile on human embryo lung (HEL) cells.
研究空心莲子草的化感作用和遗传毒性机理对于有效治理该入侵种具有十分重要的意义。
It is important significance that studied the mechanism of the allelopathy and heredity toxicity of this species to effectively control the invasive plant.
目的用碱性单细胞凝胶电泳技术检测苯作业工人外周血淋巴细胞DNA损伤，研究苯的遗传毒性。
Objective To detect DNA damage in peripheral lymphocytes of workers exposed to benzene by alkaline single cell gel electrophoresis and to study the genetic toxicity of benzene.
采用细胞体外培养的方法，在卵巢颗粒细胞对数生长期，对f - 2毒素的繁殖遗传毒性和V - E对其的解毒作用进行了研究。
During logarithmic phase of cultivated ovary granulose cell, experiments were carried out to investigate the genetically procreation toxicity of F-2 toxin and the detoxification of V-E.
研究表明，当原水中含有溴离子时，经氯化消毒、氯胺消毒或臭氧消毒后会增加溴代消毒副产物的形成，并且溴代副产物具有更高的遗传毒性。
Bromide by-products would increase after disinfection by chlorination, chloramination and ozone if containing bromine ions in raw water, and they have a higher genetic toxicity.
尽管黄酮表现出有益健康的效果，但一些研究指出了它们的诱变性和遗传毒性。
Despite the apparent beneficial health effects of flavonoids, several studies indicate th Eir mutagenicity and genotoxicity in both bacterial and mammalian experimental systems.
目的：研究盐酸川丁特罗（SPFF）的遗传毒性。
Objective:To study the genetic toxicity of tranterol hydrochloride (SPFF).
应用蚕豆根尖微核试验研究了三氯乙烯的遗传毒性。
Micronucleus test of Vicia faba root tips cell is used to research the genotoxicity of Trichloroethylene (TCE).
目的：通过研究燃汽油机动车尾气成分，及其对DNA分子的氧化损伤，在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。
Objective: the genotoxicity and its molecular mechanism of gasoline vehicle exhaust were studied through examining exhaust components and the oxidative DNA damage induced by them.
研究对二氯苯的遗传毒性作用。
对荠蓝油进行急性毒性、三项遗传毒性试验和30天喂养试验，研究荠蓝油的食品安全性毒理。
Tests of acute toxicity, three terms of hereditary toxicity and feeding test for 30d were conducted to research the food safety of Camelina sativa oil.
尽管黄酮表现出有益健康的效果，但一些研究指出了它们的诱变性和遗传毒性。
Despite the apparently beneficial health effects of flavonoids, several studies indicate their mutagenicity and genotoxicity.
利用蚕豆根尖微核技术研究了氯酸钾细胞遗传毒性和污染效应。
The genetic toxicity and pollution effects of potassium chlorate on Vicia faba root tip cells were studied by means of VAMCN.
背景与目的：研究珍珠祛斑美容片的急性毒性和遗传毒性。
BACKGROUND and AIM: to study the acute toxicity and genotoxicity of pearl anti-spot cosmetic slice.
本研究显示出了改良彗星试验在综合评价各种废水遗传毒性方面具有广阔的应用前景。
The results also revealed that the modified comet assay have broad prospects for evaluating the genotoxicity of industrial wastewater comprehensively.
目的研究香烟烟雾水溶物对雄性小鼠的生殖和遗传毒性，探讨其作用机理。
Objectives to test reproductive and genetic toxicity induced by water-soluble contents of cigarette smoke (WSCCS), and explore the mechanism.
目前有关甲醛和苯联合毒性的研究较少，对遗传毒性的联合效应研究的报道更少。
Now there are few studies on the joint toxicity of formaldehyde and benzene, especially the reports of joint genotoxicity.
方法通过石油沥青急性经口毒性、亚慢性吸入毒性及遗传毒性的实验研究，观察在该实验条件下，石油沥青对受试动物的影响。
Methods Acute oral toxicity test, subchronic inhalation toxicity test and mutagenicity test were conducted to observe the effects of petroleum asphalt in experimental animals.
为研究三氯乙烯（TCE）的遗传毒性，应用单细胞凝胶电泳法（SCGE）测定了TCE诱导人和小鼠外周血有核细胞DNA链断裂的能力。
The ability of trichloroethylene(TCE) to induce single strand breaks in peripheral lymphocytes DNA of male mice in vivo was evaluated using single cell gel electrophoresis(SCGE).
如何早期、快速地获得药物可能的毒性反应数据，是当前遗传毒理学领域的研究热点之一。
Recently, how to obtain the data of potential side effects rapidly in early phase of drug research is one of the hot points in genetic toxicology.
目的：通过研究燃汽油机动车尾气成分，及其对DNA分子的氧化损伤，在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。
Objective the genotoxicity and its molecular mechanism of diesel oil vehicle exhaust were discussed through analysing the oxidative DNA damage induced by exhaust components.
目的：通过研究燃汽油机动车尾气成分，及其对DNA分子的氧化损伤，在分子生物学水平上探讨燃汽油机动车尾气污染物的遗传毒性效应与机制。
Objective the genotoxicity and its molecular mechanism of diesel oil vehicle exhaust were discussed through analysing the oxidative DNA damage induced by exhaust components.
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