我们证明了组蛋白修饰在选择性剪接中一个直接的作用。
We demonstrated a direct role for histone modifications in alternative splicing.
有关选择性剪接的调控机制是功能基因组时代的重要前沿问题之一。
Problems about mechanisms control alternative splicing is a leading research endeavors in functional genome era.
剪接比对指的是在比对过程中考虑不同选择性剪接方式的序列比对方法。
Spliced alignment is a sequence alignment method which considers the different alternative splicing forms during alignment.
PCR和测序结果分析，发现这个非编码RNA基因通过选择性剪接产生两种不同的转录产物。
Analysis of RT-PCR and sequencing indicated that the ncRNA gene had two different transcripts through alternatively splicing pattern.
这一聚类策略能降低测序错误带来的影响，有效识别基因家族成员，并避免选择性剪接的干扰。
The clustering strategy can efficiently identify gene family and alternate splicing forms of expressed sequences. It can also reduce the adverse effects caused by sequence errors.
为对真核基因的选择性剪接形式进行准确、快速、有效的研究，提出了一种启发式多序列比对算法。
A heuristic algorithm for multiple alignment was developed to more effectively study alternative splicing patterns of eukaryotic genes.
在外显子水平，共有85个发生选择性剪接的外显子，分别属于85个转录本，仅有36个已知基因。
On exon level, 85 PSRs (probe select regions) were identified as alternatively spliced exons that belonged to 85 ASTs (alternatively spliced transcripts), and 36 transcripts have an-notation.
目的探讨人结肠癌组织中是否存在环加氧酶2 (COX 2)选择性剪接异构体的表达及其可能意义。
Objective To explore the expression of cyclooxygenase 2 (COX 2) alternative splice variant in human colon cancer tissue and its possible significance.
人类的基因中，超过50%的转录产物进行选择性剪接，而这机制和疾病发生、治疗方法有高度的相关性。
Alternative splicing is generally believed to occur more than 50% of actively transcribed human genes and thus is highly relevant to disease and therapy.
人类的基因中，超过50%的转录产物进行选择性剪接，而这机制和疾病发生、治疗方法有高度的相关性。
Alternative splicing is generally believed to occur more than 50% of actively transcribed human genes and thus is highly relevant to disease and therapy.
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