方法全基因组扫描和连锁分析技术。
方法运用小家系资料连锁分析参数的方法。
Methods the parameter linkage analysis of the small pedigree data was used.
主要指标LOD值，STR位点，连锁分析。
VNTR区是连锁分析和个体鉴别的有效遗传标志。
The VNTR regions are informative genetic markers for linkage mapping and individual identification.
结果多位点连锁分析比两位点连锁分析基因定位更精确。
Results the multipoint linkage analysis could more accurately localize the disease gene than the two_point linkage analysis.
连锁分析的另一种重要统计方法是生病同胞对法(asp)。
Another important method of linkage analysis is the Affected Sib Pair (ASP).
对于无倒位的家系，利用基因多态性进行遗传连锁分析较为有效可行。
For families without inversions, it is easier and more cost-effective to undertake linkage analysis of genetic polymorphism based on PCR.
综合运用参数和非参数连锁分析，将致病基因定位到5号染色体和12号染色体上。
The disease gene is exactly located on the chromosome 5 and chromosome 12 through parameter and non-parameter linkage analysis.
目的：基因多态和疾病的连锁分析是目前研究多基因疾病分子生物学基础的常用方法。
Objective:The linkage analysis of gene polymorphism and diseases is the common method to study the molecular biological base of multigenic diseases.
基于连锁分析的QTL作图是研究复杂性状的有效手段，但其尚存在一定的局限性。
Quantitative trait loci (QTL) mapping is an important tool for studying complex traits. However, because of its limitations, QTL mapping is used only in certain cases.
方法：在有左室发育不全和二叶式主动脉瓣先证者的家系中进行非参数基因组连锁分析。
Methods: Family - based nonparametric genome - wide linkage analysis was performed in by either an HLHS or BAV proband.
因此它们可以作为进行生产性状与标记间连锁分析的遗传标记，用于进一步的QTL定位研究。
So they can be used as the linkage analyse between the production traits and makers, and used for further location of QTL.
在人类单位点致病基因与遗传标记基因的遗传连锁分析中，家系是应用得最普遍的一种群体结构。
Pedigree is one of the most general population structure in the genetic linkage analysis between human single genetic inheritance disease locus and genetic marker locus.
目的应用遗传连锁分析方法对X连锁型视网膜色素变性家系进行分析，确定其致病基因的所在位点。
Objective to identify the disease locus in X - linked retinitis pigmentosa (XLRP) families using genetic linkage analysis.
迄今为止，用连锁分析和细胞遗传学方法对小眼球相关基因进行了基因定位并进一步对候选基因进行突变分析。
Up to date, on the bases of linkage analysis and cytogenetic analysis, the loci associated with microphthalmia have been identified and mutation analysis of the candidate loci are performed.
遗传学的连锁分析是指通过遗传重组来研究染色体的结构，定位基因的位置，并确定基因在染色体上的排列顺序。
Genetic analysis of linkage used recombination to analyze the structure of chromosomes, to determine the locations of genes and their linear order along a chromosome.
结论D 12s1686位点具有较高的杂合度和多态信息含量，在基因连锁分析和群体遗传学研究中具有重要的应用价值。
Conclusion: D12S1686 is such a valuable genetic marker that it can be used to gene linkage analysis and population genetics research.
用传统的家系连锁分析无法对精神分裂症这样的复杂疾病进行基因定位，而全基因组关联分析则为最终发现这些基因提供了较好的策略。
After linkage analysis failed to locate susceptible genes of complex diseases like schizophrenia, it is a better way to process whole-genome association studies.
结论适用于小家系资料的多位点连锁分析，不仅能算出致病基因与标记的重组率和遗传距离，而且能把致病基因定位至遗传标记的一侧。
Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.
如果你在几个主要的连锁超市购买蜂蜜，分析发现如果你选购的蜂蜜品牌标有“有机”字样，你的蜂蜜很可能比较好，因为没经过超滤。
And if you have to buy at major grocery chains, the analysis found that your odds are somewhat better of getting honey that wasn't ultra-filtered if you buy brands labeled as organic.
如果说2009年的环境政策被12月进行的哥本哈根气候变化问题谈判的连锁反应所主导的话，那么2010年的环境政策则会由哥本哈根公布的分析报告所主导。
If environmental politics in 2009 were dominated by the build-up to the December Copenhagen climate-change negotiations, in 2010 they will be dominated by post-Copenhagen analysis.
分析将含义赋予工件(2)。例如，连锁餐馆15和38在甜点方面收到的投诉最多，而连锁餐馆27在最后一次问卷调查中投诉比前一次减少了一半。
The analysis assigns meaning to the artifacts (2). For example, stores 15 and 38 have the most complaints about the desserts, while store 27 has reduced its complaints by half since the last survey.
分析人士认为，安全担忧和不断上升的各种成本正在产生连锁反应的风险，导致大量韩国企业撤离开城。
Analysts said safety fears and rising costs are creating the risk of a domino effect, in which companies pull out of the complex en masse.
面对销售额的长期下降，大型连锁超市开始重启价格大战，分析师说，此举将进一步减少它们的利润。
Faced with chronic declines in sales, top supermarket chains have resorted to an all-out price war, which, according to analysts, is cutting further into their earnings.
他们也使用了一种分析方法，能够将连锁效应包括在内，计算出女性就业的整体影响。
They also used an analytic method that allowed them to calculate the total effect of maternal employment taking into account all knock-on effects.
哈里斯和他的同事们运用尼尔森公司和阿比创有限公司得出的研究数据，对12家快餐连锁公司，包括汉堡王，塔可钟，肯德基和麦当劳所播出的广告进行分析。
Using data from The Nielsen Company and Arbitron inc., Harris and her colleagues analyzed ads aired by 12 chains, including Burger King, Taco Bell, KFC and McDonald's.
分析师表示，沃尔玛连锁店一系列价格回落对交易影响有限。
The analyst said the chain's string of rollbacks, or price cuts, seemed to have a "limited impact" on traffic.
“以前，我们不太看好这支股，因为公司将太多的资金投入到开办新的连锁店，”摩根斯丹利投资银行的零售分析家格雷葛利•莫利奇（GregoryMelich）这样说。
“We used to be quite negative on the stock, because the company threw too much money at new stores, ” says Gregory Melich, a retail analyst at Morgan Stanley, an investment bank.
结合连锁餐饮品牌空间的一体化设计实践，分析这种工作模式如何使品牌形象内涵在各种形式下得到最大价值的体现。
Combined with integration design of chain dining brand, it analyzed the greatest value of brand image reflected in various forms.
连锁不平衡分析是对基因(或已定位的高分辨率QTL)的功能进行鉴定的有效方法。
Linkage disequilibrium analysis is a effective way to identify the function of the of the gene (or targeted high-resolution QTL).
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