方法采用反相高效液相色谱法对30例肿瘤患者静脉滴入MTX（1．0-3．0／次）后的脑脊液和血浆中MTX浓度进行连续测定。
Methods: MTX at a high dose ranging from 1.0 to 3.0 g per course was intravenously administered to 30 patients with malignant tumors.
方法采用反相高效液相色谱法对30例肿瘤患者静脉滴入MTX（1．0-3．0／次）后的脑脊液和血浆中MTX浓度进行连续测定。
Methods: MTX at a high dose ranging from 1.0 to 3.0 g per course was intravenously administered to 30 patients with malignant tumors.
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