方法:采用溶剂法制备固体分散体,进行溶解度、溶出速率测定,导数热重分析(DTG)。
Methods: the solid dispersion was prepared by solvent method. The solubility, the dissolution rate and the derivative thermogravimetry (DTG) were determined.
方法:以聚乙烯吡咯烷酮(PVP)、聚乙二醇-6000(PEG-6000)为载体,溶剂法和溶剂熔融法制备固体分散体,并进行体外溶出度研究。
Method: carvedilol solid dispersions were prepared by solvent-melting and coevaporation methods with PEG-6000 and PVP as carriers, the study on the dissolution was conducted in vitro.
方法:将冰片用水溶性辅料聚乙二醇6000制成固体分散体,并填装入胶囊,进行毒理试验。
Method: Bomeolum Syntheticum and PEG 6000 mixing preparative solid dispersion and packed capsules, toxicity was tested.
方法以不同分子量不同比例的聚乙二醇为载体,以熔融法制备固体分散体,并进行体外溶出度研究和DSC扫描。
METHODS Preparing the solid dispersion by melting method at different drug-to-PEG ratios with different PEG moleculars and studying the preparation with dissolution rate in vitro and DSC method.
方法选用聚乙二醇为载体,采用溶剂-熔融法制备依托度酸固体分散体,通过差热分析对固体分散体进行鉴定。
Methods Etodolac solid dispersion was prepared with PEG as carrier by solvent-fusion method and identified by differential thermal analysis.
方法选用聚乙二醇为载体,采用溶剂-熔融法制备依托度酸固体分散体,通过差热分析对固体分散体进行鉴定。
Methods Etodolac solid dispersion was prepared with PEG as carrier by solvent-fusion method and identified by differential thermal analysis.
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