这是一个大问题，因为脏水会导致疾病。
This is a huge problem because dirty water can create illnesses.
这是一个大问题，值得深思。
所以，这是一个大问题。
这是一个大问题，无论是发送和接收的。
It is a big problem for both the sender and for the receiver.
这是一个大问题到今天。
听起来是老生常谈，但是这是一个大问题。
我认为这是一个大问题，比我们想得还要大。
另外，我们也不知道谁会认为这是一个大问题。
Further, we don't know who would be viewing this as a big deal.
因为这是一个大问题。
我知道这是一个大问题，但是稍微思考一下。
这是一个大问题，也是我个人争战的一个问题。
This is a big problem and one I personally struggle with as well.
这是一个大问题。
这是一个大问题。
这是一个大问题，因为它散发出刺激性或有毒烟雾。
This is a big problem, because it gives off irritating or toxic fumes.
如果这是一个大问题，因为你的焦点意图不可动摇四出。
If so this is a big issue as your focus of intent must not be swayed hither and thither.
佛罗里达州水族馆的员工告诉福克斯13，这是一个大问题。
Staff at the Florida Aquarium told FOX 13 that's a big concern.
现在轮到你了，这是一个大问题，我知道……但是你感到幸福吗？
Over to you now. It's a big question, I know... but do you feel happy?
当你早就在一个金融网站上投入100万美元时，这是一个大问题。
That's a problem when you've already spent a million dollars on a Web site predicated on the financial markets.
有多少此类的危机会突然爆发，外界会否乐意帮助它们，这是一个大问题。
One big question is how many such crises will flare up, and how willing outsiders will be to deal with them.
“所有的球员都希望能参加这场比赛，这是一个大问题，但是个好问题。”拉法表示。
"All of the players are desperate to play in this game, which is a big problem for me but a nice one," admits the Liverpool boss.
应用程序是感知不到触发器的存在的，因此也不知道他们运行了还是没有，这是一个大问题。
A big problem with database triggers is that the application does not know that they exist, therefore does not know whether they have run or not.
我们总是相信，专家比我们高明。我们花钱让那些人告诉我们该怎么做。这是一个大问题，带来恶劣的结果。
Our willingness to believe that we can hire some expert to tell us how to outperform markets is a big problem, with big consequences.
在早期的三维游戏中这不是个大问题，但在新制作的游戏中这是一个大问题，所以让我们看看怎么来处理它。
In early 3dgames this was not a big issue, but in next generation games this is a big issue, so let's see what we can do about that.
互动设计师想到了这个问题，因为他认为这是一个大问题，同时，工业设计师也在观察，哈，那个显示器的角度什么？
That's what is going to the interaction designer's mind because that's a huge issue the industrial designer, meanwhile, is looking at huh, what's the Angle of that display?
一个大问题就是这是否已经发生过——我们的宇宙是被设计好的宇宙吗？
The big question is whether that has already happened - is our universe a designer universe?
另外还有一个大问题，这部电话在美国暂时还用不了，也没有说什么时候能在美利坚发布。这是为什么，诺基亚，你到底是告诉我这为么？
There is one big problem. This phone is not available in the States, nor has it even been announced that it will eventually come here. Why, Nokia, why?
这是个大问题，我没有一个对任何人都适用的简单答案。
This is a big question, and I don't have a single answer for everyone.
这是个大问题，我没有一个对任何人都适用的简单答案。
This is a big question, and I don't have a single answer for everyone.
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