• 高效液相色谱法测得它载药量为7.2%。

    The drug loading of the Hep-CPT conjugate was 7.2%.

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  • 吸水载药量包封吸水微球

    Compared to microspheres with low water absorbing rate, the high batches had higher drug-loading rate and entrapment rate.

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  • 研究发现改进乳化交联能获得药量较高的明胶微球。

    The drug load in microspheres was enhanced by a modified emulsion crosslink method.

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  • 结论我们制备出了稳定药量较大、包封率较高脂质体

    Conclusion: Our prepared liposome shows larger loading capacity and better envelopment and stability.

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  • 摘要:本文研究了响应法优化柿叶总黄酮缓释载药量

    Abstract: Response surface methodology was applied to optimize the drug loading rate of persimmon leaf total flavonoids sustained release pellets.

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  • 纳米粒药量、大小分布形态体外释放等进行研究。

    The drug loading, entrapment efficiency, diameter of nanoparticles and particle diameter distribution, shape and release curve of nanoparticles were investigated in vitro.

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  • 提 高了纳米粒子药量包封控制水性药物现象。

    The invention improves the carrier and packing rate of nanometer particles, and controls the instant release condition of hydrophobic drug.

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  • 考察载药量、填充种类用量、硬度、辅料粒径等因素药物释放影响

    Factors influencing the drug release rate, including drug loading, species and amount of additives, hardness, particle size were studied.

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  • 取代相对分子质量同时,随着投料增加,药量增加而包封降低

    Higher feed ratio could lead to higher loading capacity and lower encapsulation efficiency under the same degree of substitution of cholesteryl moiety and molecular weights of parent pullulan.

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  • 结果表明,所得微球粒径适合分布均匀,性质稳定药量比较适宜。

    The results showed that the particle size and distribution was suitable, quality was stable, drug-loaded and entrapment rate were fine.

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  • 模拟不同药量药物释放速率影响其它数据进行比较,以此验证模型

    The effects of different drug loadings on the drug release rate were simulated and compared with other data to validate this model.

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  • 进行了灯盏花壳聚糖纳米粒封率、药量体外释放度稳定性等试验研究。

    The entrapment efficiency, drug load content, in vitro release and stability of Bre-CS-NP were studied.

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  • 同时,不同形貌聚醚-聚酸酐三元共聚物胶束效率载药量有明显差别。

    Considered the application in nanomedicine, the effect of the diverse morphologies on drug loading efficiency was also investigated.

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  • 同时药物最终释放效率来看载药量高,纳米管中的药物残留也相对越多。

    Besides, from the view of the efficiency of drug release, the higher content of the drug loading, the more the drug residues in the nano-tubes relatively.

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  • 结果表明:碳包铁吸附性能反应条件影响较大温度载药量对释放率有一定的影响

    It was found that the influence of the reaction condition was great, for temperature and MMC loading quantity both affected the action of the desorption.

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  • 目的优化阿昔洛韦白蛋白制备工艺形态学性质、载药量体外释药进行考察

    OBJECTIVE To study the preparation of aciclovir loaded albumin microspheres (ACV BSA MS) and evaluate its morphology, drug loading and release in vitro.

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  • 琼脂凝胶电泳分析体与DNA结合力,通过紫外分光光度计检测载药量和包埋率;

    The potential of adsorbing DNA on nanoparticles was analyzed by agarose gel electrophoresis and spectrophotometer.

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  • 目的考察聚乳酸相对分子量对利福平聚乳酸形态载药量微球中药物分布状态影响

    Aim To discover the effect of molecular weight of polylactic acid on the shape, drug content and drug distribution state of rifampicin polylactic acid microspheres.

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  • 本文研究了反相高效液相色谱超速冷冻离心测定雷公藤素聚乳酸纳米粒率和药量方法

    The encapsulation efficiency and drug loading of triptolide-loaded poly (d, L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study.

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  • 初步分析表明,聚合物残留的微小杂质的影响,造成了所制备的微球低的载药量包封率。

    The results indicated that the microspheres had poor drug loading and entrapment efficiency abilities due to residual impurities contained in polymer.

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  • 方法制备左氧氟沙星-壳聚糖缓释微球药量43.88%,体外累积释放度的线形关系良好

    The drug-loading rate of this chitosan-levofloxacin sustained-release microsphere is 43.88%. Its in vitro dissolubility is good.

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  • 利用正交实验设计优选纳米球制备工艺,观测纳米球的形貌粒径药量响应体外药性能。

    The orthogonal experimental design was applied to optimize the preparation procedure. The shape, size, drug content, magnetic responsivity and drug release in vitro were determined.

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  • 发明制备工艺简单,所 得纳米粒子粒径均匀粒度分布较窄水性药物较高药量包封

    The invention has simple process, uniform grain diameter, narrow graininess distribution, high carrier and packing rate on hydrophobic drug.

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  • 方法:观察组鼠涂抹脂质体毒素混悬液(载药量0.5%),对照组大鼠涂抹0.5%鬼臼毒素酊剂

    Methods 0.5% podophyllotoxin in liposome suspension or in alcohol solution (as control) were applied on the rat skin respectively.

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  • 研究发现只有加入适量乙醇作为药物颗粒预处理才能形态圆整、粒径均一具有较高载药量球。

    Results showed that only when the CH331 particles were pretreated with a suitable amount of ethanol could lead to more uniform sizes, better appearance and higher drug loading for the microspheres.

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  • 方法采用薄膜分散法冻干工艺进行木犀草素质体制备,并载药量封率为评价指标,优化制备处方和工艺。

    Optimization of preparation and formulation was accomplished by evaluating the drug-loading amounts and the entrapment efficiency of luteolin liposomes.

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  • 方法采用溶剂-非溶剂法制维生素C微囊,制成缓释片剂采用紫外分光光度测定药量采用测定体外释放特性。

    METHODS Use solvent-non-methods to prepare vitamin C sustained-release tablets, UV method was used to determine its content and the in vitro release rate was determined by rotate basket method.

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  • 通过透射电镜观察、动态光散射测定紫外吸光度测定等手段分析微观形态粒径大小药量、测定了药胶束的体外释药速率

    Microscopic morphology, diameter and drug-loaded amount of the micelles were examined by means of TEM, DLS and UV respectively, and their in vitro drug release rates were measured.

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  • 体外溶出实验中对阿霉素磁性毫微粒体外释放性能影响主要考察了三个因素:毫微粒平均粒径大小、毫微粒的载药量以及交联剂含量

    In the drug release kinetics investigation, influences of the content of drug, the microsphere size and the content of crossing-linker on the drug-release were studied.

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  • 体外溶出实验中对阿霉素磁性毫微粒体外释放性能影响主要考察了三个因素:毫微粒平均粒径大小、毫微粒的载药量以及交联剂含量

    In the drug release kinetics investigation, influences of the content of drug, the microsphere size and the content of crossing-linker on the drug-release were studied.

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