不同的处理过程对样品的载药率也有一定的影响。
Samples of different processing on drug-loading rate has a certain influence.
该制备方法简单易行,载药率高,成本低,可实现自动化和规模化生产。
The preparation method has the advantages of simplicity, easy operation, high ratio of drug loading and low cost, and can realize automated and large-scale production.
结果被动载药法得到的包封率仅有13.3%,主动载药法的包封率最高可达84 . 6 %。
RESULTS The entrapment efficiency with passive loading was only 13.3%; while up to 84.6% with active loading method.
结果被动载药法制备脂质体包封率较低,主动载药制备脂质体包封率为84.38%。
ResultsThe entrapment efficiency with passive loading method was low, while up to 84.38% with active loading method.
初步分析表明,因聚合物中残留的微小杂质的影响,造成了所制备的载药微球过低的载药量及包封率。
The results indicated that the microspheres had poor drug loading and entrapment efficiency abilities due to residual impurities contained in polymer.
目的采用主动载药法制备硫酸长春新碱脂质体,考察包封率的影响因素。
OBJECTIVE To prepare vincristine sulfate liposomes by active loading method, and study the influence of different factors on the entrapment efficiency.
本发明方法建立的给药系统具有载药范围广、药物包封率高及稳定性好的特点,并可降低药物毒性。
The drug delivery system established by the method has the characteristics of wide drug-carrying range, high drug envelopment rate and good stability and can reduce drug toxicity.
目的制备包封率较高的氟尿嘧啶聚己内酯微球并研究不同粒径载药微球的性质。
OBJECTIVE To prepare 5-fluorouracil loaded polycaprolactone (PCL) microspheres and study the characteristics of microspheres within different sizes.
目的制备包封率较高的氟尿嘧啶聚己内酯微球并研究不同粒径载药微球的性质。
OBJECTIVE To prepare 5-fluorouracil loaded polycaprolactone (PCL) microspheres and study the characteristics of microspheres within different sizes.
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