实验结果表明N-乳糖酰壳聚糖是ASGPR的特异性配基,对肝细胞具有“主动”靶向作用,可作为肝靶向载体。
The results indicated that N-Lactosyl-Chitosan was a good ligand for ASGPR, and could be used as hepatic targeting carrier of antitumor drugs.
方法将特异性引物从S8546病毒感染细胞PCR扩增的产物克隆于T载体,正确的克隆纯化后测序,应用DNASTAR软件比较分析。
Methods RT PCR products were amplified from S85 46 virus infected cells, cloned into T vector, sequenced and analyzed using DNASTAR software.
结论:重组表达载体PGL3 - DF 3 - DTA能对DF 3阳性的乳腺癌细胞产生特异性杀伤作用。
Conclusion: Recombinant expression vector PGL3-DF3-DTA could produce specific lethal effect on human breast cancer cell line of DF3 positive.
免疫毒素是近年来新兴的一种特异性靶向治疗药物,由毒素蛋白和载体两部分构成。
Immunotoxin is a novel class of targeted agents in recent years, which is composed of toxin fragment and antibody or cytokine.
干细胞在体外可以诱导为具有肝细胞功能的细胞,可作为研究肝细胞分化机制,对HBV的特异性受体的研究载体。
Stem cells can be induced into functional liver cell in vitro, the model could serve as a vehicle to study the development of liver cell and the HBV-specific receptor research.
结论重组表达载体PGL3 -DF 3 - DTA能对DF 3阳性的乳腺癌细胞产生特异性杀伤作用。
Conclusion the recombinant expression vector PGL3-DF3-DTA can produce a specific killing effect on the DF3-positive human breast cancer cell line.
方法设计出针对各片段的特异性引物,用P CR方法从Z 37病毒感染的细胞提取细胞总rna,逆转录扩增、产物克隆t载体,纯化后测序,测定的序列应用DNASTAR软件比较分析。
Methods the total RNA was extracted from Z37 virus infected cells and the RT-PCR products were cloned into t vector, sequenced and analyzed by DNASTAR software.
马杜霉素是一种新型的聚醚类离子载体型抗生素,可以特异性的杀灭和抑制对畜牧养殖业危害极大的动物寄生虫——球虫。
Maduramicin is a new type of polyether ionophore antibiotic, which can particularly kill and restrain coccidia - a kind of animal parasite which induce coccidiosis.
利用组合库和噬菌体展示技术,我们证明半抗原特异性抗体确实存在有外围载体的某些遗迹。
By using combinatorial library and phage display technologies on a hapten-specific antibody we were able to demonstrate that a peripheral carrier imprint indeed exists.
结论:构建的心肌特异性表达腺病毒载体可使外源基因在心肌细胞内特异性表达。
Conclusion: the established viral vector AdmlcGFP allows heart specific expression of a foreign gene.
结论:肝癌特异性多柔比星免疫磷脂纳米粒,有可能成为一种新的药物靶向载体系统。
Conclusion: Doxorubicin phospholipid nanoparticle is able to become a new drug targeting carrier system.
但要想得到高表达量的特异性抗体还需要对表达载体、免疫过程等方面进一步优化。
But to get high expression levels of specific antibody expression vector, further optimization of the immune processes will be also needed.
本发明具有作为乳腺癌靶向性基因治疗的特异性载体的潜在临床应用价值。
The invention as a specificity carrier of the mammary cancer-targeting genetic therapy has potential clinic application value.
结论载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白d1的表达和激活。
Conclusion Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line.
结论载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白d1的表达和激活。
Conclusion Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line.
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